Re-evaluating circuit mechanisms underlying pattern separation

NA Cayco-Gajic, RA Silver - Neuron, 2019 - cell.com
When animals interact with complex environments, their neural circuits must separate
overlapping patterns of activity that represent sensory and motor information. Pattern …

On simplicity and complexity in the brave new world of large-scale neuroscience

P Gao, S Ganguli - Current opinion in neurobiology, 2015 - Elsevier
Technological advances have dramatically expanded our ability to probe multi-neuronal
dynamics and connectivity in the brain. However, our ability to extract a simple conceptual …

Deep supervised, but not unsupervised, models may explain IT cortical representation

SM Khaligh-Razavi, N Kriegeskorte - PLoS computational biology, 2014 - journals.plos.org
Inferior temporal (IT) cortex in human and nonhuman primates serves visual object
recognition. Computational object-vision models, although continually improving, do not yet …

Cortical population activity within a preserved neural manifold underlies multiple motor behaviors

JA Gallego, MG Perich, SN Naufel, C Ethier… - Nature …, 2018 - nature.com
Populations of cortical neurons flexibly perform different functions; for the primary motor
cortex (M1) this means a rich repertoire of motor behaviors. We investigate the flexibility of …

Extracting spatial–temporal coherent patterns in large-scale neural recordings using dynamic mode decomposition

BW Brunton, LA Johnson, JG Ojemann… - Journal of neuroscience …, 2016 - Elsevier
Background There is a broad need in neuroscience to understand and visualize large-scale
recordings of neural activity, big data acquired by tens or hundreds of electrodes recording …

A neural algorithm for a fundamental computing problem

S Dasgupta, CF Stevens, S Navlakha - Science, 2017 - science.org
Similarity search—for example, identifying similar images in a database or similar
documents on the web—is a fundamental computing problem faced by large-scale …

A category-free neural population supports evolving demands during decision-making

D Raposo, MT Kaufman, AK Churchland - Nature neuroscience, 2014 - nature.com
The posterior parietal cortex (PPC) receives diverse inputs and is involved in a dizzying
array of behaviors. These many behaviors could rely on distinct categories of neurons …

[HTML][HTML] Accurate estimation of neural population dynamics without spike sorting

EM Trautmann, SD Stavisky, S Lahiri, KC Ames… - Neuron, 2019 - cell.com
A central goal of systems neuroscience is to relate an organism's neural activity to behavior.
Neural population analyses often reduce the data dimensionality to focus on relevant activity …

Imaging beam‐sensitive materials by electron microscopy

Q Chen, C Dwyer, G Sheng, C Zhu, X Li… - Advanced …, 2020 - Wiley Online Library
Electron microscopy allows the extraction of multidimensional spatiotemporally correlated
structural information of diverse materials down to atomic resolution, which is essential for …

On staying grounded and avoiding quixotic dead ends

LW Barsalou - Psychonomic bulletin & review, 2016 - Springer
The 15 articles in this special issue on The Representation of Concepts illustrate the rich
variety of theoretical positions and supporting research that characterize the area. Although …