Early lung cancer detection

T Inage, T Nakajima, I Yoshino… - Clinics in chest …, 2018 - chestmed.theclinics.com
Lung cancer is the leading cause of cancer death worldwide with an overall 5-year survival
rate of 18.1%. 1 Despite investigation of lung cancer genetics and improvements in …

Metabolomic fingerprinting for the detection of early-stage lung cancer: from the genome to the metabolome

JF Haince, P Joubert, H Bach, R Ahmed Bux… - International Journal of …, 2022 - mdpi.com
The five-year survival rate of lung cancer patients is very low, mainly because most newly
diagnosed patients present with locally advanced or metastatic disease. Therefore, early …

Detection technologies of volatile organic compounds in the breath for cancer diagnoses

T Le, R Priefer - Talanta, 2023 - Elsevier
Although there are new approaches in both cancer treatment and diagnosis, overall
mortality is a major concern. New technologies have attempted to look at breath volatile …

Exhaled breath condensate biomarkers for lung cancer

A Campanella, S De Summa… - Journal of breath …, 2019 - iopscience.iop.org
Lung cancer is the main cause of cancer incidence and mortality worldwide and the
identification of clinically useful biomarkers for lung cancer detection at both early and …

[HTML][HTML] Molecular biomarkers in early stage lung cancer

M Rodríguez, D Ajona, LM Seijo, J Sanz… - … lung cancer research, 2021 - ncbi.nlm.nih.gov
Low dose computed tomography (LDCT) screening, together with the recent advances in
targeted and immunotherapies, have shown to improve non-small cell lung cancer (NSCLC) …

Targeting KRAS mutant lung cancer cells with siRNA-loaded bovine serum albumin nanoparticles

A Mehta, E Dalle Vedove, L Isert, OM Merkel - Pharmaceutical research, 2019 - Springer
Purpose KRAS is the most frequently mutated gene in human cancers. Despite its direct
involvement in malignancy and intensive effort, direct inhibition of KRAS via …

[HTML][HTML] Early diagnosis and screening in lung cancer

C Cainap, LA Pop, O Balacescu… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Lung cancer is the third most diagnosed cancer, but the first cause of cancer-related deaths
worldwide. This rather high death rate is due mainly to the fact that most patients are …

miR-196b promotes lung cancer cell migration and invasion through the targeting of GATA6

H Li, C Feng, S Shi - Oncology letters, 2018 - spandidos-publications.com
MicroRNAs (miRNAs) have been proven to regulate gene expression at the protein
translation level. miRNA abnormal expression has been associated with the development of …

Clinical utility of microRNAs in exhaled breath condensate as biomarkers for lung cancer

C Pérez-Sánchez, N Barbarroja, LC Pantaleão… - Journal of personalized …, 2021 - mdpi.com
This study represents a novel proof of concept of the clinical utility of miRNAs from exhaled
breath condensate (EBC) as biomarkers of lung cancer (LC). Genome-wide miRNA profiling …

Non-coding RNAs and nuclear architecture during epithelial-mesenchymal transition in lung cancer and idiopathic pulmonary fibrosis

K Rubio, R Castillo-Negrete, G Barreto - Cellular Signalling, 2020 - Elsevier
Lung cancer (LC) is the leading cause of cancer-related deaths worldwide. On the other
hand, idiopathic pulmonary fibrosis (IPF) is the most common interstitial lung disease …