Bone tissue engineering: Anionic polysaccharides as promising scaffolds

PM Sivakumar, AA Yetisgin, SB Sahin, E Demir… - Carbohydrate …, 2022 - Elsevier
Bone repair is a self-healing process. However, critical-sized bone defects need bone
augmentation where bone tissue engineering plays vital role. Bone tissue Engineering …

A review of recent advances in natural polymer-based scaffolds for musculoskeletal tissue engineering

J Fan, K Abedi-Dorcheh, A Sadat Vaziri… - Polymers, 2022 - mdpi.com
The musculoskeletal (MS) system consists of bone, cartilage, tendon, ligament, and skeletal
muscle, which forms the basic framework of the human body. This system plays a vital role in …

Biomaterials for soft tissue repair and regeneration: A focus on italian research in the field

MC Bonferoni, C Caramella, L Catenacci, B Conti… - Pharmaceutics, 2021 - mdpi.com
Tissue repair and regeneration is an interdisciplinary field focusing on developing bioactive
substitutes aimed at restoring pristine functions of damaged, diseased tissues. Biomaterials …

Orthobiologics: a review

AF Mavrogenis, V Karampikas, A Zikopoulos… - International …, 2023 - Springer
Purpose The use of biologic materials in orthopaedics (orthobiologics) has gained
significant attention over the past years. To enhance the body of the related literature, this …

Aligned ice templated biomaterial strategies for the musculoskeletal system

F Diaz, N Forsyth, AR Boccaccini - Advanced Healthcare …, 2023 - Wiley Online Library
Aligned pore structures present many advantages when conceiving biomaterial strategies
for treatment of musculoskeletal disorders. Aligned ice templating (AIT) is one of the many …

Advanced graft development approaches for ACL reconstruction or regeneration

O Urbanek, M Moczulska-Heljak, M Wróbel… - Biomedicines, 2023 - mdpi.com
The Anterior Cruciate Ligament (ACL) is one of the major knee ligaments, one which is
greatly exposed to injuries. According to the British National Health Society, ACL tears …

Toward the Improvement of the Mechanical and Tribological Properties of Braided Ligament for ACL Reconstruction: A “Carrot and Stick” Strategy

S Li, S Wang, J Shao, J Wang, W Liu… - Advanced …, 2024 - Wiley Online Library
Bone tunnel enlargement has been troubling the clinical adoption of braided artificial
ligaments for decades, to which mechanical and tribological performance promotion shall be …

Mimicking the graded wavy structure of the anterior cruciate ligament

S Camarero‐Espinosa, H Yuan… - Advanced …, 2023 - Wiley Online Library
Anterior cruciate ligament (ACL) is the connective tissue providing mechanical stability to the
knee joint. ACL reconstruction upon rupture remains a clinical challenge due to the high …

Reproduction of the mechanical behavior of ligament and tendon for artificial joint using bioinspired 3d braided fibers

X Lu, L Ren, K Wang, G Wei, Z Qian… - … on Neural Systems …, 2022 - ieeexplore.ieee.org
The level of joint laxity, which is an indicator of accurate diagnosis for musculoskeletal
conditions is manually determined by a physician. Studying joint laxity via artificial joints is …

Directing ligament-mimetic bi-directional cell organization in scaffolds through zone-specific microarchitecture for ligament tissue engineering

M Sriram, S Priya, A Mahajan, DS Katti - Biofabrication, 2024 - iopscience.iop.org
Ligament tissues exhibit zone-specific anisotropic cell organization. The cells in ligament-
proper are longitudinally oriented, whereas, the cells in epiligament are circumferentially …