3D traction force microscopy in biological gels: from single cells to multicellular spheroids
Cell traction force plays a critical role in directing cellular functions, such as proliferation,
migration, and differentiation. Current understanding of cell traction force is largely derived …
migration, and differentiation. Current understanding of cell traction force is largely derived …
Multiphoton intravital microscopy of rodents
CLGJ Scheele, D Herrmann, E Yamashita… - Nature Reviews …, 2022 - nature.com
Tissues are heterogeneous with respect to cellular and non-cellular components and in the
dynamic interactions between these elements. To study the behaviour and fate of individual …
dynamic interactions between these elements. To study the behaviour and fate of individual …
[HTML][HTML] Identification of CD44 as a key engager to hyaluronic acid-rich extracellular matrices for cell traction force generation and tumor invasion in 3D
BCH Cheung, X Chen, HJ Davis, CS Nordmann, J Toth… - Matrix Biology, 2025 - Elsevier
Mechanical properties of the extracellular matrix (ECM) critically regulate a number of
important cell functions including growth, differentiation and migration. Type I collagen and …
important cell functions including growth, differentiation and migration. Type I collagen and …
Rear cortex contraction aids in nuclear transit during confined migration by increasing pressure in the cell posterior
As cells migrate through biological tissues, they must frequently squeeze through micron-
sized constrictions in the form of interstitial pores between extracellular matrix fibers and/or …
sized constrictions in the form of interstitial pores between extracellular matrix fibers and/or …
[HTML][HTML] A Novel Single-Color FRET Sensor for Rho-Kinase Reveals Calcium-Dependent Activation of RhoA and ROCK
AE Mancini, MA Rizzo - Sensors, 2024 - mdpi.com
Ras homolog family member A (RhoA) acts as a signaling hub in many cellular processes,
including cytoskeletal dynamics, division, migration, and adhesion. RhoA activity is tightly …
including cytoskeletal dynamics, division, migration, and adhesion. RhoA activity is tightly …
[PDF][PDF] CD44 and beta1-integrin are both engaged in cell traction force generation in hyaluronic acid-rich extracellular matrices
Mechanical properties of the extracellular matrices (ECMs) critically regulate a number of
important cell function including growth, differentiation and migration. Type I collagen and …
important cell function including growth, differentiation and migration. Type I collagen and …
Unravelling molecular dynamics in living cells: Fluorescent protein biosensors for cell biology
C Sanchez, A Ramirez, L Hodgson - Journal of Microscopy, 2024 - Wiley Online Library
Genetically encoded, fluorescent protein (FP)‐based Förster resonance energy transfer
(FRET) biosensors are microscopy imaging tools tailored for the precise monitoring and …
(FRET) biosensors are microscopy imaging tools tailored for the precise monitoring and …
[HTML][HTML] Desmosomal Cadherin Tension Loss in Pemphigus Vulgaris Mediated by the Inhibition of Active RhoA at Cell-Cell Adhesions
X Jin, J Rosenbohm, AO Moghaddam, E Kim… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Binding of autoantibodies to keratinocyte surface antigens, primarily desmoglein 3 (Dsg3) of
the desmosomal complex, leads to the dissociation of cell-cell adhesion in the blistering …
the desmosomal complex, leads to the dissociation of cell-cell adhesion in the blistering …
Identification of CD44 as a key mediator of cell traction force generation in hyaluronic acid-rich extracellular matrices
BCH Cheung, X Chen, HJ Davis, CS Nordmann, J Toth… - bioRxiv, 2023 - biorxiv.org
Mechanical properties of the extracellular matrices (ECMs) critically regulate a number of
important cell function including growth, differentiation and migration. Type I collagen and …
important cell function including growth, differentiation and migration. Type I collagen and …
Roles of Hyaluronic Acid in Tumor Mechanics and Invasion
B Cheung - 2024 - search.proquest.com
Cells interact with the extracellular matrix (ECM) mechanically to perform essential cell
function including migration, proliferation and differentiation, which are critical in …
function including migration, proliferation and differentiation, which are critical in …