Unresolved inflammation is a key mediator of advanced heart failure. Especially, damage,
pathogen, and lifestyle-associated molecular patterns are the major factors in initiating …

The CCL2-CCR2 axis is one of the major chemokine signaling pathways that has received
special attention because of its function in the development and progression of …

Inflammation has been recognized as a major pathophysiological contributor to the entire
spectrum of human heart failure (HF), including HF with reduced ejection fraction, HF with …

Background: Recent studies have established that CCR2 (CC chemokine receptor type 2)
marks proinflammatory subsets of monocytes, macrophages, and dendritic cells that …

Innate immune cells are the early responders to infection and tissue damage. They play a
critical role in the initiation and resolution of inflammation in response to insult as well as …

Cardiac hypertrophy, initiated by a variety of physiological or pathological stimuli
(hemodynamic or hormonal stimulation or infarction), is a critical early adaptive …

Global vaccination effort and better understanding of treatment strategies provided a ray of
hope for improvement in COVID-19 pandemic, however, in many countries, the disease …

Diabetic cardiomyopathy (DCM) is a myocardial disease independent of other
cardiovascular diseases, such as coronary heart disease, hypertension, etc. Lipotoxicity is …

Heart failure (HF) characterized by cardiac remodeling is a condition in which inflammation
and fibrosis play a key role. Dietary supplementation with n-3 polyunsaturated fatty acids …

Macrophages are essential components of the immune system and play a role in the normal
functioning of the cardiovascular system. Depending on their origin and phenotype, cardiac …