Brain imaging genomics: integrated analysis and machine learning
L Shen, PM Thompson - Proceedings of the IEEE, 2019 - ieeexplore.ieee.org
Brain imaging genomics is an emerging data science field, where integrated analysis of
brain imaging and genomics data, often combined with other biomarker, clinical, and …
brain imaging and genomics data, often combined with other biomarker, clinical, and …
Genetic and environmental influences on neuroimaging phenotypes: a meta-analytical perspective on twin imaging studies
GAM Blokland, GI de Zubicaray… - Twin Research and …, 2012 - cambridge.org
Because brain structure and function are affected in neurological and psychiatric disorders,
it is important to disentangle the sources of variation in these phenotypes. Over the past 15 …
it is important to disentangle the sources of variation in these phenotypes. Over the past 15 …
A meta‐analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the …
Schizophrenia is associated with widespread alterations in subcortical brain structure. While
analytic methods have enabled more detailed morphometric characterization, findings are …
analytic methods have enabled more detailed morphometric characterization, findings are …
Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease
In a genome-wide association study of structural brain degeneration, we mapped the 3D
profile of temporal lobe volume differences in 742 brain MRI scans of Alzheimer's disease …
profile of temporal lobe volume differences in 742 brain MRI scans of Alzheimer's disease …
Genetics of microstructure of cerebral white matter using diffusion tensor imaging
We analyzed the degree of genetic control over intersubject variability in the microstructure
of cerebral white matter (WM) using diffusion tensor imaging (DTI). We performed heritability …
of cerebral white matter (WM) using diffusion tensor imaging (DTI). We performed heritability …
Early-emerging sulcal patterns are atypical in fetuses with congenital heart disease
Fetuses with congenital heart disease (CHD) have third trimester alterations in cortical
development on brain magnetic resonance imaging (MRI). However, the intersulcal …
development on brain magnetic resonance imaging (MRI). However, the intersulcal …
Sex differences in brain structure in auditory and cingulate regions
We applied a new method to visualize the three-dimensional profile of sex differences in
brain structure based on MRI scans of 100 young adults. We compared 50 men with 50 …
brain structure based on MRI scans of 100 young adults. We compared 50 men with 50 …
Genetics of primary cerebral gyrification: Heritability of length, depth and area of primary sulci in an extended pedigree of Papio baboons
Genetic control over morphological variability of primary sulci and gyri is of great interest in
the evolutionary, developmental and clinical neurosciences. Primary structures emerge …
the evolutionary, developmental and clinical neurosciences. Primary structures emerge …
Logical circularity in voxel‐based analysis: Normalization strategy may induce statistical bias
Recent discussions within the neuroimaging community have highlighted the problematic
presence of selection bias in experimental design. Although initially centering on the …
presence of selection bias in experimental design. Although initially centering on the …
Applying tensor-based morphometry to parametric surfaces can improve MRI-based disease diagnosis
Many methods have been proposed for computer-assisted diagnostic classification. Full
tensor information and machine learning with 3D maps derived from brain images may help …
tensor information and machine learning with 3D maps derived from brain images may help …