Exploring diseases/traits and blood proteins causally related to expression of ACE2, the putative receptor of SARS-CoV-2: a Mendelian randomization analysis …
OBJECTIVE COVID-19 has become a major public health problem. There is good evidence
that ACE2 is a receptor for SARS-CoV-2, and high expression of ACE2 may increase …
that ACE2 is a receptor for SARS-CoV-2, and high expression of ACE2 may increase …
Data-driven hypothesis weighting increases detection power in genome-scale multiple testing
Hypothesis weighting improves the power of large-scale multiple testing. We describe
independent hypothesis weighting (IHW), a method that assigns weights using covariates …
independent hypothesis weighting (IHW), a method that assigns weights using covariates …
A practical guide to methods controlling false discoveries in computational biology
Background In high-throughput studies, hundreds to millions of hypotheses are typically
tested. Statistical methods that control the false discovery rate (FDR) have emerged as …
tested. Statistical methods that control the false discovery rate (FDR) have emerged as …
MultipleTesting. com: A tool for life science researchers for multiple hypothesis testing correction
O Menyhart, B Weltz, B Győrffy - PloS one, 2021 - journals.plos.org
Scientists from nearly all disciplines face the problem of simultaneously evaluating many
hypotheses. Conducting multiple comparisons increases the likelihood that a non-negligible …
hypotheses. Conducting multiple comparisons increases the likelihood that a non-negligible …
Bayesian inference and testing of group differences in brain networks
Bayesian Inference and Testing of Group Differences in Brain Networks Page 1 Bayesian Analysis
(2018) 13, Number 1, pp. 29–58 Bayesian Inference and Testing of Group Differences in Brain …
(2018) 13, Number 1, pp. 29–58 Bayesian Inference and Testing of Group Differences in Brain …
Slotting metabolomics into routine precision medicine
Introduction Despite an impressive amount of metabolomics studies in animal models and
humans, most findings have not yet translated into the clinical setting, and the road ahead …
humans, most findings have not yet translated into the clinical setting, and the road ahead …
[HTML][HTML] Network classification with applications to brain connectomics
While statistical analysis of a single network has received a lot of attention in recent years,
with a focus on social networks, analysis of a sample of networks presents its own …
with a focus on social networks, analysis of a sample of networks presents its own …
DeepLINK: Deep learning inference using knockoffs with applications to genomics
We propose a deep learning–based knockoffs inference framework, DeepLINK, that
guarantees the false discovery rate (FDR) control in high-dimensional settings. DeepLINK is …
guarantees the false discovery rate (FDR) control in high-dimensional settings. DeepLINK is …
Covariate-assisted ranking and screening for large-scale two-sample inference
Two-sample multiple testing has a wide range of applications. The conventional practice first
reduces the original observations to a vector of p-values and then chooses a cut-off to adjust …
reduces the original observations to a vector of p-values and then chooses a cut-off to adjust …
A direct approach to estimating false discovery rates conditional on covariates
Modern scientific studies from many diverse areas of research abound with multiple
hypothesis testing concerns. The false discovery rate (FDR) is one of the most commonly …
hypothesis testing concerns. The false discovery rate (FDR) is one of the most commonly …