Sequencing of Circulating Cell-free DNA during Pregnancy | New England Journal of Medicine
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With a high sensitivity and specificity, non‐invasive prenatal testing (NIPT) is an
incomparable screening test for fetal aneuploidy. However, the method is rather newly …

Importance Understanding the relationship between aneuploidy detection on noninvasive
prenatal testing (NIPT) and occult maternal malignancies may explain results that are …

Prenatal testing for chromosomal abnormalities is designed to provide an accurate
assessment of a patient's risk of carrying a fetus with a chromosomal disorder. A wide variety …

Background Since its debut in 2011, cell-free fetal DNA screening has undergone rapid
expansion with respect to both utilization and coverage. However, conclusive data regarding …

Whole-genome sequencing (WGS) of maternal plasma cell-free DNA (cfDNA) can
potentially evaluate all 24 chromosomes to identify abnormalities of the placenta, fetus, or …

No. 348-Joint SOGC-CCMG Guideline: Update on Prenatal Screening for Fetal Aneuploidy, Fetal
Anomalies, and Adverse Pregnancy Out Page 1 JOINT SOGC-CCMG CLINICAL PRACTICE …

Fetal aneuploidies are among the most common causes of miscarriages, perinatal mortality
and neurodevelopmental impairment. During the last 70 years, many efforts have been …

The mechanisms responsible for twinning and disorders of twin gestations have been the
subject of considerable interest by physicians and scientists, and cases of atypical twinning …

Objective Direct chromosome preparations of chorionic villus samples (CVS) and cell‐free
DNA (cfDNA) testing both involve analysis of the trophoblastic cell lineage. The aim of this …