Throughout life, T cells coordinate multiple aspects of adaptive immunity, including
responses to pathogens, allergens, and tumors. In mouse models, the role of T cells is …

The discovery of T cells resident in diverse tissues has altered our understanding of
adaptive immunity to encompass site-specific responses mediated by tissue-adapted …

SARS-CoV-2 infection of children leads to a mild illness and the immunological differences
with adults are unclear. Here, we report SARS-CoV-2 specific T cell responses in infected …

Our current knowledge of human memory CD8+ T cells is derived largely from studies of the
intravascular space. However, emerging data are starting to challenge some of the dogmas …

Resident memory T cells are non-recirculating memory T cells that persist long-term in
epithelial barrier tissues, including the gastrointestinal tract, lung, skin, and reproductive …

A large proportion of memory T cells disseminated throughout the body are non‐
recirculating cells whose maintenance and function is regulated by tissue‐specific …

Intensified efforts to promote protective T cell-based immunity in vaccines and
immunotherapies have created a compelling need to expand our understanding of human T …

Memory T cells are fundamental to maintain immune surveillance of the human body. During
the past decade, it has become apparent that non-recirculating resident memory T cells …

Mucosal-associated invariant T (MAIT) cells represent a class of antimicrobial innate-like T
cells that have been characterized in human blood, liver, lungs, and intestine. Here, we …

Disruption of T cell memory during severe immune suppression results in reactivation of
chronic viral infections, such as Epstein Barr virus (EBV) and Cytomegalovirus (CMV). How …