Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America
and affects ca. 10 million people worldwide. About 30% of Chagas disease patients develop …

Pro-inflammatory cytokines are crucial for fighting infection and establishing immunity.
Recently, other proteins, such as danger-associated molecular patterns (DAMPs), have also …

Several theories exist to explain differential clinical evolution of Chagas disease. A coherent
understanding of these theories will certainly aid in determining what combination of them …

The pathogenesis of Chagas disease cardiomyopathy (CCC) is not well understood. Since
studies show that myocarditis is more frequent during the advanced stages of the disease …

Chagas disease, a neglected disease caused by the protozoan Trypanosoma cruzi, is
endemic in 21 Latin American countries, affecting 6–8 million people. Increasing numbers of …

Chagas disease is a complex tropical pathology caused by the kinetoplastid Trypanosoma
cruzi. This parasite displays massive genetic diversity and has been classified by …

Abstract Interleukin-1β (IL-1β) activates inflammatory mediator cascades and has been
implicated in the pathogenesis of several diseases. Single nucleotide polymorphisms …

There is an increasing evidence linking dysbalance between various proinflammatory
mediators and higher risk of cardiovascular events and pathologies. Likewise, some of the …

Chagas disease, which is caused by the flagellate parasite Trypanosoma cruzi, affects 8–10
million people in Latin America. The disease is endemic and is characterised by acute and …

Objective There is strong evidence that genetic as well as environmental factors affect the
development of periodontitis. Various studies suggest that genetic polymorphisms of the …