Hepatic stellate cell exosome-derived circWDR25 promotes the progression of hepatocellular carcinoma via the miRNA-4474-3P-ALOX-15 and EMT axes
L Liu, R Liao, Z Wu, C Du, Y You, K Que, Y Duan… - BioScience …, 2022 - jstage.jst.go.jp
Recently, the emerging role of circular RNAs (circRNAs) in tumor development and
progression has been a topic of great interest. Nevertheless, the effects of hepatic stellate …
progression has been a topic of great interest. Nevertheless, the effects of hepatic stellate …
Molecular mechanism and potential therapeutic targets of liver metastasis from gastric cancer
D Li, X Zhang, L Jiang - Frontiers in Oncology, 2022 - frontiersin.org
Gastric cancer (GC) is characterized by high invasion and poor prognosis. The occurrence
of liver metastasis seriously affects advanced GC prognosis. In recent years, great progress …
of liver metastasis seriously affects advanced GC prognosis. In recent years, great progress …
Deciphering the possible reciprocal loop between hepatic stellate cells and cancer cells in the tumor microenvironment of the liver
D Ezhilarasan, M Najimi - Critical Reviews in Oncology/Hematology, 2023 - Elsevier
Activated hepatic stellate cells (HSCs)/myofibroblasts are the important sources of cancer-
associated fibroblasts in the liver tumor microenvironment (TME). The crosstalk between …
associated fibroblasts in the liver tumor microenvironment (TME). The crosstalk between …
Pregnane X receptor inhibits the transdifferentiation of hepatic stellate cells by down-regulating periostin expression
T Sato, R Shizu, R Baba, A Ooka, T Hosaka… - Biochemical …, 2024 - portlandpress.com
Pregnane X receptor (PXR) is a xenobiotic-sensing nuclear receptor that plays a key role in
drug metabolism. Recently, PXR was found to attenuate the development of liver cancer by …
drug metabolism. Recently, PXR was found to attenuate the development of liver cancer by …
Circulating circRNA: a social butterfly in tumors
S Miao, Q Zhang - Frontiers in Oncology, 2023 - frontiersin.org
Circular RNAs (circRNAs) are a class of single-stranded non-coding RNAs that form circular
structures through irregular splicing or post-splicing events. CircRNAs are abnormally …
structures through irregular splicing or post-splicing events. CircRNAs are abnormally …
[HTML][HTML] Combination of transcatheter arterial chemoembolization and anti-PD-L1 liposomes therapy suppressed hepatocellular carcinoma progression in mice
J Li, L Zhang, Y Tao, Z Sun, Y Ge, S Hu - European Journal of …, 2023 - Elsevier
Background Hepatocellular carcinoma (HCC) is a serious life-threatened tumor with high
morbidity and mortality. This study aimed to study the effects of combination TACE and anti …
morbidity and mortality. This study aimed to study the effects of combination TACE and anti …
[HTML][HTML] CCL16 inhibits tumor proliferation and metastasis in HCC by impacting CK19 phenotype
H Li, J Zhuo, P Zhang, J Chen, Z Lin, X Yang, R Zhao… - iLIVER, 2024 - Elsevier
Background and aims Cytokeratin 19–positive (CK19+) hepatocellular carcinoma (HCC) is
an aggressive subtype with poor outcomes. The initiation and development of CK19+ HCC …
an aggressive subtype with poor outcomes. The initiation and development of CK19+ HCC …
The Role of the Lysine-Specific Demethylase 1 in the Development of Hepatocellular Carcinoma
J Wang - 2022 - kups.ub.uni-koeln.de
Hepatocellular carcinoma (HCC) has a low survival rate and is currently the third leading
cause of cancer-related deaths worldwide. Most HCC develops on the basis of chronic liver …
cause of cancer-related deaths worldwide. Most HCC develops on the basis of chronic liver …