[HTML][HTML] Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies
NC Noronha, A Mizukami, C Caliári-Oliveira… - Stem cell research & …, 2019 - Springer
Multipotent mesenchymal stromal cells (MSC) have been widely explored for cell-based
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …
Engineering multi‐cellular spheroids for tissue engineering and regenerative medicine
Multi‐cellular spheroids are formed as a 3D structure with dense cell–cell/cell–extracellular
matrix interactions, and thus, have been widely utilized as implantable therapeutics and …
matrix interactions, and thus, have been widely utilized as implantable therapeutics and …
Engineering extracellular vesicles by three‐dimensional dynamic culture of human mesenchymal stem cells
Human mesenchymal stem cell (hMSC) derived extracellular vesicles (EVs) have shown
therapeutic potential in recent studies. However, the corresponding therapeutic components …
therapeutic potential in recent studies. However, the corresponding therapeutic components …
Living and injectable porous hydrogel microsphere with paracrine activity for cartilage regeneration
X Li, X Li, J Yang, J Lin, Y Zhu, X Xu, W Cui - Small, 2023 - Wiley Online Library
Paracrine is an important mechanism in mesenchymal stem cells (MSCs) that promotes
tissue regeneration. However, anoikis is attributed to unsuitable adhesion microenvironment …
tissue regeneration. However, anoikis is attributed to unsuitable adhesion microenvironment …
Spheroid culture of mesenchymal stem cells
Z Cesarz, K Tamama - Stem cells international, 2016 - Wiley Online Library
Compared with traditional 2D adherent cell culture, 3D spheroidal cell aggregates, or
spheroids, are regarded as more physiological, and this technique has been exploited in the …
spheroids, are regarded as more physiological, and this technique has been exploited in the …
Engineered biomaterials to guide spheroid formation, function, and fabrication into 3D tissue constructs
N Di Caprio, JA Burdick - Acta biomaterialia, 2023 - Elsevier
Cellular spheroids are aggregates of cells that are being explored to address fundamental
biological questions and as building blocks for engineered tissues. Spheroids possess …
biological questions and as building blocks for engineered tissues. Spheroids possess …
Combination of 3D printing and electrospinning techniques for biofabrication
DL Yang, F Faraz, JX Wang… - Advanced Materials …, 2022 - Wiley Online Library
This review presents the different combination methods of 3D printing and electrospinning
processes and discusses the advantages of each method. Also, the applications of products …
processes and discusses the advantages of each method. Also, the applications of products …
Stromal cells and stem cells in clinical bone regeneration
Stem-cell-mediated bone repair has been used in clinical trials for the regeneration of large
craniomaxillofacial defects, to slow the process of bone degeneration in patients with …
craniomaxillofacial defects, to slow the process of bone degeneration in patients with …
MSC spheroids-loaded collagen hydrogels simultaneously promote neuronal differentiation and suppress inflammatory reaction through PI3K-Akt signaling pathway
J He, N Zhang, Y Zhu, R Jin, F Wu - Biomaterials, 2021 - Elsevier
It is critical for the clinical success to take the anti-inflammatory function into consideration
when integrating the neurogenesis into the nerve repair materials. To this aim, we prepared …
when integrating the neurogenesis into the nerve repair materials. To this aim, we prepared …
[HTML][HTML] Increased mesenchymal stem cell functionalization in three-dimensional manufacturing settings for enhanced therapeutic applications
D Kouroupis, D Correa - Frontiers in bioengineering and …, 2021 - frontiersin.org
Mesenchymal stem/stromal cell (MSC) exist within their in vivo niches as part of
heterogeneous cell populations, exhibiting variable stemness potential and supportive …
heterogeneous cell populations, exhibiting variable stemness potential and supportive …