Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of 'stress' …

This review discusses the formation of hypochlorous acid HOCl and the role of reactive
chlorinated species (RCS), which are catalysed by the enzyme myeloperoxidase MPO …

Rationale: Extracellular DNA (eDNA) and neutrophil extracellular traps (NETs) are
implicated in multiple inflammatory diseases. NETs mediate inflammasome activation and IL …

Objective Myocardial infarction (MI) is a leading cause of mortality and morbidity worldwide
and new treatment strategies are highly sought-after. Paradoxically, reperfusion of the …

The heme protein myeloperoxidase (MPO) is a major constituent of neutrophils. As a key
mediator of the innate immune system, neutrophils are rapidly recruited to inflammatory …

Inflammation plays a very important role in the pathogenesis of various diseases like
atherosclerosis, rheumatoid arthritis, asthma, and cancer. Lack of anti-inflammatory drugs …

Normal or “good” inflammation process starts from a local cellular response against injury or
any infectious agent, with the activation of neutrophils, macrophages, Langerhans cells …

Cells are subjected to endogenous [eg, reactive oxygen species (ROS), replication stress]
and exogenous insults (eg, UV light, ionizing radiation, and certain chemicals), which can …

Knee osteoarthritis (KOA) is a chronic multifactorial pathology and a current and essential
challenge for public health, with a negative impact on the geriatric patient's quality of life …

Electronic cigarettes or e-cigarettes are the most frequently used tobacco product among
adolescents. Despite the widespread use of e-cigarettes and the known detrimental cardiac …