Thrombospondins are evolutionarily conserved, calcium-binding glycoproteins that undergo
transient or longer-term interactions with other extracellular matrix components. They share …

The formation of the musculoskeletal system represents an intricate process of tissue
assembly involving heterotypic inductive interactions between tendons, muscles and …

Tendons and ligaments are extracellular matrix (ECM)-rich structures that interconnect
muscles and bones. Recent work has shown how tendon fibroblasts (tenocytes) interact with …

The molecular signals driving tendon development are not fully identified. We have
undertaken a transcriptome analysis of mouse limb tendon cells that were isolated at …

The molecular programme underlying tendon development has not been fully identified.
Interactions with components of the musculoskeletal system are important for limb tendon …

Drosophila Vago is a small antiviral peptide. Its ortholog in Culex mosquito was found to be
an interferon-like cytokine that limits virus replication through activating Jak/Stat signaling …

The myotendinous junction (MTJ) is a complex specialized region located at the muscle-
tendon interface that represents the primary site of force transmission. Despite their different …

Tendon is a uniaxial connective tissue component of the musculoskeletal system. Tendon is
involved in force transmission between muscle and bone. Tendon injury is very common …

Cell-extracellular matrix interactions have been studied extensively using cells cultured in
vitro. These studies indicate that focal adhesion (FA)-based cell-extracellular matrix …

Tendons are extracellular matrix (ECM)-rich structures that mediate muscle attachments with
the skeleton, but surprisingly little is known about molecular mechanisms of attachment …