Latin American populations, characterized by intricate admixture patterns resulting from the
intermingling of ancestries from European, Native American (NA) Asian, and African …

Ultraviolet radiation (UV) is causally linked to cutaneous melanoma, yet the underlying
epigenetic mechanisms, known as molecular sensors of exposure, have not been …

Colorectal cancer (CRC) caused 261,060 deaths in Brazil over a 20-year period, with a
tendency to increase over time. This study aimed to verify the sociodemographic factors …

Colorectal cancer (CRC) has a high incidence and mortality worldwide. Microsatellite
instability (MSI) is crucial in CRC, with distinct molecular and clinicopathological features in …

We evaluated the prevalence of pathogenic/likely pathogenic germline variants (PGV) in
Brazilian pancreatic adenocarcinoma (PC) patients, that represent a multiethnic population …

Purpose Breast cancer molecular subtypes show significant differences in different ethnic
groups in the United States, but no study has evaluated genetic ancestry in breast cancer in …

The heterogeneity of Myelodysplastic Neoplasm (MDS) extends beyond mutational diversity
to include significant ethnic variability, a factor that has been underexplored. While the …

Escherichia coli has been associated with the induction of colorectal cancer (CRC). Thus,
combined therapy incorporating usnic acid (UA) and antibiotics such as ceftazidime (CAZ) …

Tobacco-or human papillomavirus-driven oropharyngeal squamous cell carcinomas
(OpSCC) represent distinct clinical, biological and epidemiological entities. The aim of this …

Background Most colorectal cancers (CRC) arise from precursor lesions. This study aimed to
characterize the mutation profile of colorectal cancer precursor lesions in a Brazilian …