Advances in pharmacological activities of terpenoids

W Yang, X Chen, Y Li, S Guo… - Natural Product …, 2020 - journals.sagepub.com
Terpenoids, the most abundant compounds in natural products, are a set of important
secondary metabolites in plants with diverse structures. Terpenoids play key roles in plant …

Targeting apoptosis pathways in cancer and perspectives with natural compounds from mother nature

FM Millimouno, J Dong, L Yang, J Li, X Li - Cancer prevention research, 2014 - AACR
Although the incidences are increasing day after day, scientists and researchers taken
individually or by research group are trying to fight against cancer by several ways and also …

Pinocembrin: a novel natural compound with versatile pharmacological and biological activities

A Rasul, FM Millimouno, W Ali Eltayb… - BioMed research …, 2013 - Wiley Online Library
Pinocembrin (5, 7‐dihydroxyflavanone) is one of the primary flavonoids isolated from the
variety of plants, mainly from Pinus heartwood, Eucalyptus, Populus, Euphorbia, and …

Sesquiterpenes and their derivatives-natural anticancer compounds: An update

T Abu-Izneid, A Rauf, MA Shariati, AA Khalil… - Pharmacological …, 2020 - Elsevier
Sesquiterpenes belong to the largest group of plant secondary metabolites, which consist of
three isoprene building units. These compounds are widely distributed in various …

[HTML][HTML] Antitumor activity and mechanism of costunolide and dehydrocostus lactone: Two natural sesquiterpene lactones from the Asteraceae family

Q Li, Z Wang, Y Xie, H Hu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Costunolide (COS) and dehydrocostus lactone (DEH) are two natural sesquiterpene
lactones with potential antitcancer activity against a range of cancer cell types both in vitro …

Costunolide—A bioactive sesquiterpene lactone with diverse therapeutic potential

DY Kim, BY Choi - International journal of molecular sciences, 2019 - mdpi.com
Sesquiterpene lactones constitute a major class of bioactive natural products. One of the
naturally occurring sesquiterpene lactones is costunolide, which has been extensively …

[HTML][HTML] Curcumol: from plant roots to cancer roots

W Wei, A Rasul, A Sadiqa, I Sarfraz… - … Journal of Biological …, 2019 - ncbi.nlm.nih.gov
Natural products, an infinite treasure of bioactive scaffolds, have provided an excellent
reservoir for the discovery of drugs since millennium. These naturally occurring, biologically …

Potential anticancer properties and mechanisms of action of formononetin

D Jiang, A Rasul, R Batool, I Sarfraz… - BioMed research …, 2019 - Wiley Online Library
Nature, a vast reservoir of pharmacologically active molecules, has been most promising
source of drug leads for the cure of various pathological conditions. Formononetin is one of …

Fusobacterium nucleatum Facilitates Apoptosis, ROS Generation, and Inflammatory Cytokine Production by Activating AKT/MAPK and NF‐κB Signaling Pathways in …

W Kang, Z Jia, D Tang, Z Zhang, H Gao… - Oxidative medicine …, 2019 - Wiley Online Library
Fusobacterium nucleatum (F. nucleatum) plays key roles in the initiation and progression of
periodontitis. However, the pathogenic effect of F. nucleatum on human oral tissues and …

Potential anti-cancer activities and mechanisms of costunolide and dehydrocostuslactone

X Lin, Z Peng, C Su - International journal of molecular sciences, 2015 - mdpi.com
Costunolide (CE) and dehydrocostuslactone (DE) are derived from many species of
medicinal plants, such as Saussurea lappa Decne and Laurus nobilis L. They have been …