Revealing lncRNA structures and interactions by sequencing-based approaches
Long noncoding RNAs (lncRNAs) have emerged as significant players in almost every level
of gene function and regulation. Thus, characterizing the structures and interactions of …
of gene function and regulation. Thus, characterizing the structures and interactions of …
Evolution to the rescue: using comparative genomics to understand long non-coding RNAs
I Ulitsky - Nature Reviews Genetics, 2016 - nature.com
Long non-coding RNAs (lncRNAs) have emerged in recent years as major players in a
multitude of pathways across species, but it remains challenging to understand which of …
multitude of pathways across species, but it remains challenging to understand which of …
RNA-mediated epigenetic regulation of gene expression
D Holoch, D Moazed - Nature Reviews Genetics, 2015 - nature.com
Diverse classes of RNA, ranging from small to long non-coding RNAs, have emerged as key
regulators of gene expression, genome stability and defence against foreign genetic …
regulators of gene expression, genome stability and defence against foreign genetic …
Technological developments in lncRNA biology
S Jathar, V Kumar, J Srivastava, V Tripathi - Long Non Coding RNA …, 2017 - Springer
It is estimated that more than 90% of the mammalian genome is transcribed as non-coding
RNAs. Recent evidences have established that these non-coding transcripts are not junk or …
RNAs. Recent evidences have established that these non-coding transcripts are not junk or …
[HTML][HTML] lincRNAs: genomics, evolution, and mechanisms
Long intervening noncoding RNAs (lincRNAs) are transcribed from thousands of loci in
mammalian genomes and might play widespread roles in gene regulation and other cellular …
mammalian genomes and might play widespread roles in gene regulation and other cellular …
On the classification of long non-coding RNAs
Long non-coding RNAs (lncRNAs) have been found to perform various functions in a wide
variety of important biological processes. To make easier interpretation of lncRNA …
variety of important biological processes. To make easier interpretation of lncRNA …
RNA structure probing uncovers RNA structure-dependent biological functions
RNA molecules fold into complex structures that enable their diverse functions in cells.
Recent revolutionary innovations in transcriptome-wide RNA structural probing of living cells …
Recent revolutionary innovations in transcriptome-wide RNA structural probing of living cells …
Genome regulation by long noncoding RNAs
The central dogma of gene expression is that DNA is transcribed into messenger RNAs,
which in turn serve as the template for protein synthesis. The discovery of extensive …
which in turn serve as the template for protein synthesis. The discovery of extensive …
[HTML][HTML] RNA duplex map in living cells reveals higher-order transcriptome structure
RNA has the intrinsic property to base pair, forming complex structures fundamental to its
diverse functions. Here, we develop PARIS, a method based on reversible psoralen …
diverse functions. Here, we develop PARIS, a method based on reversible psoralen …
Evolutionary conservation of long non-coding RNAs; sequence, structure, function
P Johnsson, L Lipovich, D Grandér… - Biochimica et Biophysica …, 2014 - Elsevier
Background Recent advances in genomewide studies have revealed the abundance of long
non-coding RNAs (lncRNAs) in mammalian transcriptomes. The ENCODE Consortium has …
non-coding RNAs (lncRNAs) in mammalian transcriptomes. The ENCODE Consortium has …