The modern western diet rich in advanced glycation end-products (AGEs): An overview of its impact on obesity and early progression of renal pathology

A Bettiga, F Fiorio, F Di Marco, F Trevisani, A Romani… - Nutrients, 2019 - mdpi.com
Advanced glycation end-products (AGEs) are an assorted group of molecules formed
through covalent bonds between a reduced sugar and a free amino group of proteins, lipids …

Association of metabolic syndrome and chronic kidney disease

FG Scurt, MJ Ganz, C Herzog, K Bose… - Obesity …, 2024 - Wiley Online Library
The prevalence of kidney disease is increasing rapidly worldwide, reflecting rising rates of
obesity, diabetes, and associated metabolic syndrome (MetS). Chronic kidney disease and …

Trimethylamine N-oxide binds and activates PERK to promote metabolic dysfunction

S Chen, A Henderson, MC Petriello, KA Romano… - Cell metabolism, 2019 - cell.com
The gut-microbe-derived metabolite trimethylamine N-oxide (TMAO) is increased by insulin
resistance and associated with several sequelae of metabolic syndrome in humans …

Increased renal cellular senescence in murine high-fat diet: effect of the senolytic drug quercetin

SR Kim, K Jiang, M Ogrodnik, X Chen, XY Zhu… - Translational …, 2019 - Elsevier
Obesity and dyslipidemia can be associated with cellular senescence, and may impair
kidney function. However, whether senescence contributes to renal dysfunction in these …

Association of the metabolic syndrome with mortality and major adverse cardiac events: a large chronic kidney disease cohort

LM Pammer, C Lamina, UT Schultheiss… - Journal of Internal …, 2021 - Wiley Online Library
Background Metabolic syndrome with its key components insulin resistance, central obesity,
dyslipidaemia, and hypertension is associated with a high risk for cardiovascular events and …

Prevalence and associations of metabolic syndrome in patients with alcohol use disorder

A Hernández-Rubio, A Sanvisens, F Bolao… - Scientific reports, 2022 - nature.com
Excessive alcohol consumption has been associated with different components of the
metabolic syndrome (MetS) such as arterial hypertension, dyslipidemia, type 2 diabetes or …

Novel insights in the physiopathology and management of obesity-related kidney disease

J Sandino, M Martín-Taboada, G Medina-Gómez… - Nutrients, 2022 - mdpi.com
Obesity is recognized as an independent risk factor for the development of kidney disease,
which has led to the designation of obesity-related glomerulopathy (ORG). Common renal …

Comparison of various obesity-related indices for identification of metabolic syndrome: a population-based study from Taiwan biobank

TH Chiu, YC Huang, H Chiu, PY Wu, HYC Chiou… - Diagnostics, 2020 - mdpi.com
This study aimed to evaluate the performance of 11 obesity-related indices, including body
mass index (BMI), waist circumference, waist-to-height ratio, waist–hip ratio, a body shape …

The association of metabolic syndrome components and chronic kidney disease in patients with hypertension

K Xie, L Bao, X Jiang, Z Ye, J Bing, Y Dong… - Lipids in health and …, 2019 - Springer
Background Hypertension is a highly prevalent disease and the leading cause of chronic
kidney disease (CKD). Metabolic syndrome could also be the risk factor for CKD. We sought …

NLRP3 inflammasome in metabolic-associated kidney diseases: an update

W Xiong, XF Meng, C Zhang - Frontiers in immunology, 2021 - frontiersin.org
Metabolic syndrome (MS) is a group of complex metabolic disorders syndrome, which refers
to the pathological state of metabolism disorder of protein, fat, carbohydrate and other …