Lipids can undergo modification as a result of interaction with reactive oxygen species
(ROS). For example, lipid peroxidation results in the production of a wide variety of highly …

Breast cancer (BC) is the most common malignancy responsible for the largest number of
deaths in women worldwide. The risk of developing BC is predisposed by many factors such …

Background We previously reported higher plasma levels of complement fragments C3a
and C5a in neovascular Age-related Macular Degeneration (nAMD) patients with macular …

Retinal inflammation underlies multiple prevalent retinal diseases. While microglia are one
of the most studied cell types regarding retinal inflammation, growing evidence shows that …

Blood–retinal barrier (BRB) dysfunction underlies macular oedema in many sight-
threatening conditions, including diabetic macular oedema, neovascular age-related …

Diabetic retinopathy (DR) is characterised by dysfunction of the retinal neurovascular unit,
leading to visual impairment and blindness. Müller cells are key components of the retinal …

Vascular endothelial growth factor‐C (VEGF‐C) binds to receptor vascular endothelial
growth factor receptor‐3 (VEGFR‐3) expressed on lymphatic endothelial and melanoma …

To investigate the mechanism of vascular endothelial growth factor (VEGF) and brain-
derived neurotrophic factor (BDNF) in Müller cell (MC) viability and neuroprotection in …

Diabetic retinopathy (DR) is a complication of diabetes mellitus that can lead to vision loss
and blindness. It is driven by various biochemical processes and molecular mechanisms …

The pro-inflammatory cytokines secreted by Müller cells aggregate retinal cell loss and
vascularization in diabetic retinopathy (DR). The deubiquitinase BRCA1-BRCA2-containing …