Autophagosomes are double-membrane vesicles newly formed during autophagy to engulf
a wide range of intracellular material and transport this autophagic cargo to lysosomes (or …

Autophagy is a highly conserved catabolic process induced under various conditions of
cellular stress, which prevents cell damage and promotes survival in the event of energy or …

Arp2/3 complex is an actin filament nucleation and branching machinery conserved in all
eukaryotes from yeast to human. Arp2/3 complex branched networks generate pushing …

Symmetric cell division requires the even partitioning of genetic information and cytoplasmic
contents between daughter cells. Whereas the mechanisms coordinating the segregation of …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

The actin cytoskeleton and associated motor proteins provide the driving forces for
establishing the astonishing morphological diversity and dynamics of mammalian cells …

Macroautophagy, hereafter autophagy, is a degradative process conserved among
eukaryotes, which is essential to maintain cellular homeostasis. Defects in autophagy lead …

Autophagy is a catabolic 'self-eating'pathway that is emerging as a crucial integration point
in cell physiology. With its own set of genes, the autophagy pathway communicates with …

Actin cytoskeleton dynamics play vital roles in most forms of intracellular trafficking by
promoting the biogenesis and transport of vesicular cargoes. Mounting evidence indicates …

The Arp2/3 complex is an evolutionary conserved molecular machine that generates
branched actin networks. When activated, the Arp2/3 complex contributes the actin …