The NF-κB (nuclear factor K-light-chain-enhancer of activated B cells) transcription factor
family is critical for modulating the immune proinflammatory response throughout the body …

Hypoxic-ischemic brain injury poses a significant threat to the neural niche within the central
nervous system. In response to this pathological process, microglia, as innate immune cells …

The pathogenesis of thyroid dysgenesis (TD) is not well understood. Here, using a
combination of single-cell RNA and spatial transcriptome sequencing, we identify a …

Transcriptome-wide association studies (TWAS) have been widely used to integrate
transcriptomic and genetic data to study complex human diseases. Within a test dataset …

The term glia describes a heterogenous collection of distinct cell types that make up a large
proportion of our nervous system. Although once considered the glue of the nervous system …

We previously described a nucleolar protein RSL1D1 but distributed throughout the nucleus
in HCT116 colorectal cancer (CRC) cells to facilitate G1/S transition by inhibiting p53 …

Eukaryotic ribosomes are complex molecular nanomachines translating genetic information
from mRNAs into proteins. There is natural heterogeneity in ribosome composition. The …

Objective To undertake a comprehensive assay of PDCD11 expression in colorectal cancer
(CRC) and its association with prognosis and immune cell infiltration (ICIN) utilizing …

Background/Aim: Osimertinib, a third-generation epidermal growth factor receptor tyrosine
kinase inhibitor, is a highly effective and valuable treatment option for advanced non-small …

Simple Summary Despite the recent advances in human malignancy therapy, metastasis
and chemoresistance remain the principal causes of cancer-derived deaths. Given the fatal …