Healing of cutaneous wounds is a complex and well-coordinated process requiring
cooperation among multiple cells from different lineages and delicately orchestrated …

Fibromodulin (FMOD) is an archetypal member of the class II small leucine-rich
proteoglycan family. By directly binding to extracellular matrix structural components, such …

Over the last 2 decades, induced pluripotent stem cells (iPSCs) have had various potential
applications in various medical research areas, from personalized medicine to disease …

Masquelet's induced membrane (IM) technique is a promising treatment strategy for the
repair of substantial bone defects. The formation of an IM around polymethylmethacrylate …

Oxidative stress (OS), a common intracellular phenomenon induced by excess reactive
oxygen species (ROS) generation, has been shown to be associated with mammalian …

A plethora of both acute and chronic conditions, including traumatic, degenerative,
malignant, or congenital disorders, commonly induce bone disorders often associated with …

As a leading cause of disability among adults, osteoarthritis (OA) leads to serious public
health and economic burdens. Currently, treatment options for OA are generally based on …

A central challenge in tissue engineering is obtaining a suitable cell type with a capable
delivery vehicle to replace or repair damaged or diseased tissues with tissue mimics …

Background Cardiac fibrosis is an important cause of heart failure (HF) after myocardial
infarction (MI). Cyclin-dependent kinase inhibitor 2b (CDKN2b) regulates the cell cycle by …

The Sunong black pig is a new composite breed under development generated from
Chinese indigenous pig breeds (ie, Taihu and Huai) and intensive pig breeds (ie, Landrace …