COVID-19 as part of the hyperferritinemic syndromes: the role of iron depletion therapy

C Perricone, E Bartoloni, R Bursi, G Cafaro… - Immunologic …, 2020 - Springer
SARS-CoV-2 infection is characterized by a protean clinical picture that can range from
asymptomatic patients to life-threatening conditions. Severe COVID-19 patients often display …

[HTML][HTML] Iron and liver fibrosis: Mechanistic and clinical aspects

KJ Mehta, SJ Farnaud, PA Sharp - World journal of …, 2019 - ncbi.nlm.nih.gov
Liver fibrosis is characterised by excessive deposition of extracellular matrix that interrupts
normal liver functionality. It is a pathological stage in several untreated chronic liver …

[HTML][HTML] Ellagic acid attenuates liver toxicity induced by valproic acid in rats

NF Abdelkader, M Elyamany, AM Gad, N Assaf… - Journal of …, 2020 - Elsevier
Valproic acid is a commonly used drug for many psychiatric disorders, particularly for
epilepsy. However, it has been reported that its use is associated with possible side effects …

Nonsurgical therapy for hydrocephalus: a comprehensive and critical review

MR Del Bigio, DL Di Curzio - Fluids and Barriers of the CNS, 2015 - Springer
Pharmacological interventions have been tested experimentally and clinically to prevent
hydrocephalus and avoid the need for shunting beginning in the 1950s. Clinical trials of …

Iron-induced liver injury: a critical reappraisal

SA Bloomer, KE Brown - International journal of molecular sciences, 2019 - mdpi.com
Iron is implicated in the pathogenesis of a number of human liver diseases. Hereditary
hemochromatosis is the classical example of a liver disease caused by iron, but iron is …

Ferroptosis: shedding light on mechanisms and therapeutic opportunities in liver diseases

H You, L Wang, F Bu, H Meng, C Huang, G Fang, J Li - Cells, 2022 - mdpi.com
Cell death is a vital physiological or pathological phenomenon in the development process
of the organism. Ferroptosis is a kind of newly-discovered regulated cell death (RCD), which …

Boron induces lymphocyte proliferation and modulates the priming effects of lipopolysaccharide on macrophages

I Routray, S Ali - PLoS One, 2016 - journals.plos.org
Chemical mediators of inflammation (CMI) are important in host defense against infection.
The reduced capacity of host to induce the secretion of these mediators following infection is …

Chlorogenic acid ameliorated concanavalin A-induced hepatitis by suppression of Toll-like receptor 4 signaling in mice

Y Yuan, X Gong, L Zhang, R Jiang, J Yang… - International …, 2017 - Elsevier
Chlorogenic acid (CGA), one of the most abundant dietary polyphenolic compounds, has
been reported to exhibit anti-inflammatory ability. However, the hepatoprotective effects and …

Ferroptosis and multi-organ complications in COVID-19: mechanisms and potential therapies

Q Li, Z Chen, X Zhou, G Li, C Zhang, Y Yang - Frontiers in Genetics, 2023 - frontiersin.org
COVID-19 is an infectious disease caused by SARS-CoV-2, with respiratory symptoms as
primary manifestations. It can progress to severe illness, leading to respiratory failure and …

Protective Effect of Schisandra chinensis Polysaccharides Against the Immunological Liver Injury in Mice Based on Nrf2/ARE and TLR4/NF-κB Signaling Pathway

Y Shan, B Jiang, J Yu, J Wang, X Wang, H Li… - Journal of medicinal …, 2019 - liebertpub.com
We have previously demonstrated the hepatoprotective effect of Schisandra chinensis
polysaccharides (SCP) against the liver injury induced by alcohol, high-fat diet, and carbon …