Evaluation of transcriptomic signature as a valuable tool to study drug-induced cholestasis in primary human hepatocytes

C Parmentier, P Couttet, A Wolf, T Zaccharias… - Archives of …, 2017 - Springer
Primary human hepatocyte (PHH) sandwich cultures from five different donors were daily
exposed to cyclosporine A (CsA), ibuprofen (IBU), chlorpromazine (CPZ), amiodarone (AMI) …

Inter-individual differences in the susceptibility of primary human hepatocytes towards drug-induced cholestasis are compound and time dependent

C Parmentier, DFG Hendriks, B Heyd, P Bachellier… - Toxicology letters, 2018 - Elsevier
Cholestasis represents a major subtype of drug-induced liver injury and novel preclinical
models for its prediction are needed. Here we used primary human hepatocytes (PHH) from …

Primary human hepatocyte spheroids as tools to study the hepatotoxic potential of non-pharmaceutical chemicals

V Vilas-Boas, E Gijbels, K Leroy, A Pieters… - International journal of …, 2021 - mdpi.com
Drug-induced liver injury, including cholestasis, is an important clinical issue and economic
burden for pharmaceutical industry and healthcare systems. However, human-relevant in …

Response to ciclosporin treatment in Ethiopian and Nepali patients with severe leprosy Type 1 reactions

SNS Marlowe, R Leekassa, E Bizuneh… - Transactions of the …, 2007 - academic.oup.com
Leprosy type 1 reactions (T1R) are immune-mediated events with inflammation of peripheral
nerves and skin. We report the clinical outcomes of a closely monitored open prospective …

Formulation and evaluation of patchouli oil microemulsion and microemulgel for inhibit the bacterial growth

N Suharti, RF Putri - Research Journal of Pharmacy and …, 2022 - indianjournals.com
Patchouli oil from patchouli leaves (Pogostemon cablin, Benth) is known as the antimicrobial
effect. Patchouli oil has been formulated into a gel dosage form. But the appearance of the …

Pengaruh Perbandingan Surfaktan Dan Ko-Surfaktan Terhadap Karakteristik Dan Kestabilan Mikroemulsi Minyak Zaitun (Olive Oil)

D Ratnasari, H Noviardi, BAA AR - Jurnal Farmamedika …, 2017 - ejournal.sttif.ac.id
ABSTRAK Minyak Zaitun (Olive oil) merupakan senyawa yang diketahui memiliki aktivitas
farmakologi seperti antikolesterol. Kelarutan yang rendah dari minyak zaitun menyebabkan …

PENGARUH KOMBINASI SURFAKTAN TWEEN 80 DAN SPAN 80 TERHADAP SIFAT FISIK DAN STABILITAS FISIK MIKROEMULSI ESTER VITAMIN C DAN VITAMIN …

FK Astuti - 2014 - core.ac.uk
Ester vitamin C dan vitamin E diketahui memiliki fungsi sebagai antioksidan. Campuran
ester vitamin C dan vitamin E diformulasikan dalam bentuk mikroemulsi untuk meningkatkan …

Formulasi Sediaan Mikroemulsi Topikal Vitamin C Palmitat Tipe Minyak Dalam Air

BHNS Farm - 2011 - dspace.uii.ac.id
Vitamin C palmitat merupakan bentuk derivat vitamin C (L-ascorbic acid) yang larut dalam
minyak dan mampu menembus kulit dengan baik. Tujuan penelitian ini adalah untuk …

[引用][C] ESTUDIO PARA DETERMINAR LA BIOEQUIVALENCIA DE LA CICLOSPORINA ORAL EN CAPSULAS DE 100 mg EN VOLUNTARIOS SANOS

MA CONTRERAS BARRIOS

[引用][C] Unidades Academicas: ESM

MA CONTRERAS BARRIOS