Epigenetic regulation in the tumor microenvironment: molecular mechanisms and therapeutic targets
J Yang, J Xu, W Wang, B Zhang, X Yu… - Signal transduction and …, 2023 - nature.com
Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …
Tumor immune microenvironment lncRNAs
EG Park, SJ Pyo, Y Cui, SH Yoon… - Briefings in …, 2022 - academic.oup.com
Long non-coding ribonucleic acids (RNAs)(lncRNAs) are key players in tumorigenesis and
immune responses. The nature of their cell type-specific gene expression and other …
immune responses. The nature of their cell type-specific gene expression and other …
Long noncoding RNA: a dazzling dancer in tumor immune microenvironment
Y Zhang, Q Liu, Q Liao - Journal of Experimental & Clinical Cancer …, 2020 - Springer
Long noncoding RNAs (lncRNAs) are a class of endogenous, non-protein coding RNAs that
are highly linked to various cellular functions and pathological process. Emerging evidence …
are highly linked to various cellular functions and pathological process. Emerging evidence …
miRNAs and lncRNAs as novel therapeutic targets to improve cancer immunotherapy
Simple Summary Cancer onset and progression are promoted by high deregulation of the
immune system. Recently, major advances in molecular and clinical cancer immunology …
immune system. Recently, major advances in molecular and clinical cancer immunology …
HOXA-AS2 contributes to regulatory T cell proliferation and immune tolerance in glioma through the miR-302a/KDM2A/JAG1 axis
C Zhong, B Tao, X Li, W Xiang, L Peng, T Peng… - Cell Death & …, 2022 - nature.com
Long non-coding RNAs (lncRNAs) have been manifested to manipulate diverse biological
processes, including tumor-induced immune tolerance. Thus, we aimed in this study to …
processes, including tumor-induced immune tolerance. Thus, we aimed in this study to …
Long non-coding RNAs in the tumor immune microenvironment: biological properties and therapeutic potential
YN Pi, WC Qi, BR Xia, G Lou, WL Jin - Frontiers in immunology, 2021 - frontiersin.org
Cancer immunotherapy (CIT) is considered a revolutionary advance in the fight against
cancer. The complexity of the immune microenvironment determines the success or failure …
cancer. The complexity of the immune microenvironment determines the success or failure …
The genetics of autoimmune Addison disease: past, present and future
EC Røyrvik, ES Husebye - Nature Reviews Endocrinology, 2022 - nature.com
Autoimmune Addison disease is an endocrinopathy that is fatal if not diagnosed and treated
in a timely manner. Its rarity has hampered unbiased studies of the predisposing genetic …
in a timely manner. Its rarity has hampered unbiased studies of the predisposing genetic …
Reverse-genetics studies of lncRNAs—what we have learnt and paths forward
F Gao, Y Cai, P Kapranov, D Xu - Genome biology, 2020 - Springer
Long non-coding RNAs (lncRNAs) represent a major fraction of the transcriptome in
multicellular organisms. Although a handful of well-studied lncRNAs are broadly recognized …
multicellular organisms. Although a handful of well-studied lncRNAs are broadly recognized …
IPEX syndrome: genetics and treatment options
I Ben-Skowronek - Genes, 2021 - mdpi.com
(1) Background: IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked)
syndrome characterizes a complex autoimmune reaction beginning in the perinatal period …
syndrome characterizes a complex autoimmune reaction beginning in the perinatal period …
Long non-coding RNAs (lncRNAs) in response and resistance to cancer immunosurveillance and immunotherapy
GC Eptaminitaki, N Wolff, D Stellas, K Sifakis, S Baritaki - Cells, 2021 - mdpi.com
Long non-coding RNAs (lncRNAs) are critical regulatory elements in cellular functions in
states of both normalcy and disease, including cancer. LncRNAs can influence not only …
states of both normalcy and disease, including cancer. LncRNAs can influence not only …