SUMMARY The Frank–Starling law of the heart applies to all classes of vertebrates. It
describes how stretch of cardiac muscle, up to an optimum length, increases contractility …

Thermal acclimation causes the heart of some fish species to undergo significant
remodelling. This includes changes in electrical activity, energy utilization and structural …

The determinants of relaxation in cardiac muscle are poorly understood, yet compromised
relaxation accompanies various pathologies and impaired pump function. In this study, we …

Rainbow trout remain active in waters that seasonally change between 4° C and 20° C. To
explore how these fish are able to maintain cardiac function over this temperature range we …

Ultrastructure, molecular composition and electrophysiological properties of cardiac
myocytes and functional characteristics of the fish heart suggest that cycling of extracellular …

Cardiac troponin C belongs to the EF-hand superfamily of calcium-binding proteins and
plays an essential role in the regulation of muscle contraction and relaxation. To follow …

Key points• The amount of force generated by heart cells is strongly influenced by feedback
from the deformation of cardiac tissue, both from the changes in cell length and the rate at …

ABSTRACT A decrease in environmental temperature represents a challenge to the
cardiovascular system of ectotherms. To gain insight into the cellular changes that occur …

Chronic pressure or volume overload can cause the vertebrate heart to remodel. The hearts
of fish remodel in response to seasonal temperature change. Here we focus on the passive …

Cold acclimation of zebrafish causes changes to the structure and composition of the heart.
However, little is known of the consequences of these changes on heart function or if these …