Bacterial toxins active against mosquitoes: Mode of action and resistance

MHNL Silva-Filha, TP Romão, TMT Rezende… - Toxins, 2021 - mdpi.com
Larvicides based on the bacteria Bacillus thuringiensis svar. israelensis (Bti) and
Lysinibacillus sphaericus are effective and environmentally safe compounds for the control …

[HTML][HTML] Mosquito-larvicidal Binary (BinA/B) proteins for mosquito control programs—advancements, challenges, and possibilities

M Sharma, V Kumar - Current Research in Insect Science, 2022 - Elsevier
The increasing global burden of mosquito-borne diseases require targeted, environmentally
friendly, and sustainable approaches for effective vector control without endangering the …

Functional Bacillus thuringiensis Cyt1Aa Is Necessary To Synergize Lysinibacillus sphaericus Binary Toxin (Bin) against Bin-Resistant and -Refractory Mosquito …

NA Nascimento, MC Torres-Quintero… - Applied and …, 2020 - Am Soc Microbiol
The binary (Bin) toxin from Lysinibacillus sphaericus is effective to mosquito larvae, but its
utilization is threatened by the development of insect resistance. Bin toxin is composed of …

A Culex quinquefasciatus strain resistant to the binary toxin from Lysinibacillus sphaericus displays altered enzyme activities and energy reserves

HSG Menezes, SG Costa-Latgé, FA Genta… - Parasites & …, 2023 - Springer
Background The resistance of a Culex quinquefasciatus strain to the binary (Bin) larvicidal
toxin from Lysinibacillus sphaericus is due to the lack of expression of the toxin's receptors …

Identification and characterization of long noncoding RNAs and their association with acquisition of blood meal in Culex quinquefasciatus

A Azlan, MA Halim, F Mohamad, G Azzam - Insect Science, 2021 - Wiley Online Library
Abstract The Southern house mosquito, Culex quinquefasciatus (Cx. quinquefasciatus) is an
important vector that transmit multiple diseases including West Nile encephalitis, Japanese …

Culex quinquefasciatus alpha-glucosidase serves as a putative receptor of the Cry48Aa toxin from Lysinibacillus sphaericus

Q Guo, Y Gao, C Xing, Y Niu, L Ding, X Dai - Insect Biochemistry and …, 2022 - Elsevier
Abstract The Cry48Aa/Cry49Aa toxin of Lysinibacillus sphaericus shows specific toxicity
towards larvae of Culex spp. Individual Cry48Aa and Cry49Aa subunits interact with distinct …

Culex quinquefasciatus Resistant to the Binary Toxin from Lysinibacillus sphaericus Displays a Consistent Downregulation of Pantetheinase Transcripts

TMT Rezende, HSG Menezes, AM Rezende… - Biomolecules, 2023 - mdpi.com
Culex quinquefasciatus resistance to the binary (Bin) toxin, the major larvicidal component
from Lysinibacillus sphaericus, is associated with mutations in the cqm1 gene, encoding the …

Molecular and biological features of Culex quinquefasciatus homozygous larvae for two cqm1 alleles that confer resistance to Lysinibacillus sphaericus larvicides

HSG Menezes, NA Nascimento… - Pest Management …, 2021 - Wiley Online Library
BACKGROUND Culex quinquefasciatus resistance to the binary toxin from Lysinibacillus
sphaericus larvicides can occur because of mutations in the cqm1 gene that prevents the …

Insecticides derived from natural products: diversity and potential applications

J Wahengbam, LS Bhushan, JB Patil… - Current Trends in …, 2021 - Springer
Entomopathogenic microbes viz., bacteria, actinomycetes, fungi, virus, protozoans; microbial
metabolites; phytochemicals from plants viz., neem, chrysanthemum, tobacco, derris, basil …

Cys183 and Cys258 in Cry49Aa toxin from Lysinibacillus sphaericus are essential for toxicity to Culex quinquefasciatus larvae

Q Guo, L Ding, Y Gao, Y Niu, X Dai - Archives of Microbiology, 2021 - Springer
Abstract The two-component Cry48Aa/Cry49Aa toxin produced by Lysinibacillus sphaericus
shows specifically toxic to Culex quinquefasciatus mosquito larvae. Cry49Aa C-terminal …