Recently, mesenchymal stromal cells (MSCs) and also their exosome has become a game-
changing tool in the context of tissue engineering and regenerative medicine. MSCs due to …

Mesenchymal stem/stromal cell (MSC)-based therapeutics is already available for treatment
of a range of diseases or medical conditions. Autologous or allogeneic MSCs obtained from …

Intercellular communication is a normal feature of most physiological interactions between
cells in healthy organisms. While cells communicate directly through intimate physiology …

Background Chronic nonhealing wounds represent one of the most common complications
of diabetes and require advanced treatment strategies. Increasing evidence supports the …

Critical limb ischemia (CLI), the terminal stage of peripheral arterial disease (PAD), is
characterized by an extremely high risk of amputation and vascular issues, resulting in …

Progressive peripheral arterial disease (PAD) can result in chronic limb-threatening
ischemia (CLTI) characterized by clinical complications including rest pain, gangrene and …

Chronic non-healing wounds have posed a severe threat to patients mentally and
physically. Behavior dysregulation of remaining cells at wound sites is recognized as the …

There is increasing interest in the use of adipose-derived mesenchymal stromal cells (ASCs)
for wound repair. As the fate of administered cells is still poorly defined, we aimed to …

Autologous platelet-rich plasma (au-PRP) has been widely used for the management of
refractory chronic wounds. However, patients with diabetic lower extremity ulcers (DLEUs) …

Epithelial tissue injury can occur on any surface site of the body, particularly in the skin or
urethral mucosa tissue, due to trauma, infection, inflammation, and toxic compounds. Both …