Therapeutic developments for tuberculosis and nontuberculous mycobacterial lung disease
Tuberculosis (TB) drug discovery and development has undergone nothing short of a
revolution over the past 20 years. Successful public–private partnerships and sustained …
revolution over the past 20 years. Successful public–private partnerships and sustained …
[HTML][HTML] Tuberculosis treatment monitoring tests during routine practice: study design guidance
ELH MacLean, AJ Zimmer, S den Boon… - Clinical Microbiology …, 2024 - Elsevier
Scope The current tools for tuberculosis (TB) treatment monitoring, smear microscopy and
culture, cannot accurately predict poor treatment outcomes. Research into new TB treatment …
culture, cannot accurately predict poor treatment outcomes. Research into new TB treatment …
Acetic Acid Enables Molecular Enumeration of Mycobacterium tuberculosis from Sputum and Eliminates the Need for a Biosafety Level 3 Laboratory
A Palekyte, A Morkowska, O Billington… - Clinical …, 2024 - academic.oup.com
Abstract Background Improved monitoring of Mycobacterium tuberculosis response to
treatment is urgently required. We previously developed the molecular bacterial load assay …
treatment is urgently required. We previously developed the molecular bacterial load assay …
[HTML][HTML] Accuracy of the tuberculosis molecular bacterial load assay to diagnose and monitor response to anti-tuberculosis therapy: a longitudinal comparative study …
E Musisi, S Wamutu, W Ssengooba, S Kasiinga… - The Lancet …, 2024 - thelancet.com
Background In 2018, the tuberculosis molecular bacterial load assay (TB-MBLA), a
ribosomal RNA-based test, was acknowledged by WHO as a molecular assay that could …
ribosomal RNA-based test, was acknowledged by WHO as a molecular assay that could …
Quantifying Viable M. tuberculosis Safely Obviating the Need for High Containment Facilities
Mycobacterium tuberculosis is an infectious pathogen that requires biosafety level-3
laboratory for handling. The risk of transmission is high to laboratory staff, and to manage the …
laboratory for handling. The risk of transmission is high to laboratory staff, and to manage the …