Ferroptosis, a newly emerged form of regulated necrotic cell death, has been demonstrated
to play an important role in multiple diseases including cancer, neurodegeneration, and …

Reactive oxygen species and reactive nitrogen species are biological molecules that play
important roles in cardiovascular physiology and contribute to disease initiation …

Significance: Protein S-nitrosylation, the oxidative modification of cysteine by nitric oxide
(NO) to form protein S-nitrosothiols (SNOs), mediates redox-based signaling that conveys, in …

This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

S-nitrosylation, the covalent attachment of a nitrogen monoxide group to the thiol side chain
of cysteine, has emerged as an important mechanism for dynamic, post-translational …

Protein S-nitrosylation constitutes a large part of the ubiquitous influence of nitric oxide on
cellular signal transduction and accumulating evidence indicates important roles for S …

During the past decade a plethora of studies have unravelled the multiple roles of nitric
oxide (NO) in airway physiology and pathophysiology. In the respiratory tract, NO is …

Oxidants are produced as a by-product of aerobic metabolism, and organisms ranging from
prokaryotes to mammals have evolved with an elaborate and redundant complement of …

S-Nitrosylation, the redox-based modification of Cys thiol side chains by nitric oxide, is a
common mechanism in signal transduction. Dysregulated S-nitrosylation contributes to a …

In the past few years, nuclear DNA damage-sensing mechanisms activated by ionizing
radiation have been identified, including ATM/ATR and the DNA-dependent protein kinase …