The stereocontrolled construction of C− C bonds remains one of the foremost challenges in
organic synthesis. At the heart of any chemical synthesis of a natural product or designed …

In the transition-metal-catalyzed cross-coupling reactions, the use of the first row transition
metals as catalysts is much more appealing than the precious metals owing to the apparent …

Intellectual curiosity has always been one of the major driving forces leading to new
advances in chemistry. At the onset of the 20th century, the fact that biaryls could be optically …

Organic syntheses are composed of two main types of reactions: Carbon-carbon bond
formations and functional group transformations. CC bond formation is the essence of …

A rotationally hindered and thus stereogenic biaryl axis is the structurally and
stereochemically decisive element of a steadily growing number of natural products, chiral …

Suzuki− Miyaura coupling reactions of aryl and heteroaryl halides with aryl-, heteroaryl-and
vinylboronic acids proceed in very good to excellent yield with the use of 2-(2 ', 6 ' …

The recent advent of transition‐metal mediated C H activation is revolutionizing the
synthetic field and gradually infusing a “C H activation mind‐set” in both students and …

Axially chiral biaryl structures are unique systems encountered in various synthetic
compounds such as BINAP and BINOL, polymers, but also in natural products presenting a …

Though often perceived as the simple metaphorical hybrid of synthetic inorganic and
organic chemistry, synthetic organometallic chemistry continues to vigorously differentiate …

We report efficient syntheses of axially chiral biaryl amides in yields ranging from 80− 92%,
and with enantioselectivity in the range 88− 94% ee employing an asymmetric Suzuki …