[HTML][HTML] Optical tweezers in single-molecule biophysics

CJ Bustamante, YR Chemla, S Liu… - Nature Reviews Methods …, 2021 - nature.com
Optical tweezers have become the method of choice in single-molecule manipulation
studies. In this Primer, we first review the physical principles of optical tweezers and the …

Recent advances on host–guest material systems toward organic room temperature phosphorescence

X Yan, H Peng, Y Xiang, J Wang, L Yu, Y Tao, H Li… - Small, 2022 - Wiley Online Library
The design and characterization of purely organic room‐temperature phosphorescent (RTP)
materials for optoelectronic applications is currently the focus of research in the field of …

Xanthene, cyanine, oxazine and BODIPY: the four pillars of the fluorophore empire for super-resolution bioimaging

S Samanta, K Lai, F Wu, Y Liu, S Cai, X Yang… - Chemical Society …, 2023 - pubs.rsc.org
In the realm of biological research, the invention of super-resolution microscopy (SRM) has
enabled the visualization of ultrafine sub-cellular structures and their functions in live cells at …

Chemistries for DNA nanotechnology

M Madsen, KV Gothelf - Chemical reviews, 2019 - ACS Publications
The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …

[HTML][HTML] Pursuing excitonic energy transfer with programmable DNA-based optical breadboards

D Mathur, SA Díaz, N Hildebrandt… - Chemical Society …, 2023 - pubs.rsc.org
DNA nanotechnology has now enabled the self-assembly of almost any prescribed 3-
dimensional nanoscale structure in large numbers and with high fidelity. These structures …

Toward dynamic structural biology: Two decades of single-molecule Förster resonance energy transfer

E Lerner, T Cordes, A Ingargiola, Y Alhadid, SY Chung… - Science, 2018 - science.org
BACKGROUND Biomolecular mechanisms are typically inferred from static structural
“snapshots” obtained by x-ray crystallography, nuclear magnetic resonance (NMR) …

Droplet Cas12a assay enables DNA quantification from unamplified samples at the single-molecule level

H Yue, B Shu, T Tian, E Xiong, M Huang, D Zhu… - Nano Letters, 2021 - ACS Publications
DNA quantification is important for biomedical research, but the routinely used techniques
rely on nucleic acid amplification which have inherent issues like cross-contamination risk …

Design and application of fluorescent probes to detect cellular physical microenvironments

J Ma, R Sun, K Xia, Q Xia, Y Liu, X Zhang - Chemical Reviews, 2024 - ACS Publications
The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …

[HTML][HTML] Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles

M Lu, PD Uchil, W Li, D Zheng, DS Terry, J Gorman… - Cell host & …, 2020 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) mediates
viral entry into cells and is critical for vaccine development against coronavirus disease …

Design, synthesis, and characterization of graphene–nanoparticle hybrid materials for bioapplications

PT Yin, S Shah, M Chhowalla, KB Lee - Chemical reviews, 2015 - ACS Publications
Graphene is composed of single-atom thick sheets of sp 2 bonded carbon atoms that are
arranged in a perfect two-dimensional (2D) honeycomb lattice. Because of this structure …