Streptozotocin (STZ) is the most used diabetogenic chemical for creating rat models of type
1 and type 2 diabetes. Despite~ 60 years of using STZ in animal diabetes research, some …

Animal experimentation helps us to understand human biology. Rodents and, in particular,
rats are among the most common animals used in animal experiments. Reporting data on …

Background Previous studies have shown that psilocybin has antidepressant effects. In the
current study, we aim to explore the dose effects of psilocybin on primary (major depression …

Abstract Background and Objectives Dementia and central nervous system degeneration
are common problems in aging societies with regard to the number of people affected and …

Objective To investigate how physical exercise (PE) would affect brain‐derived neurotrophic
factor (BDNF) in randomized controlled trials (RCTs) of healthy subjects. Methods Seven …

Background: The treatment of chronic refractory low back pain (LBP) is challenging.
Conservative and pharmacologic options have demonstrated limited efficacy. Spinal cord …

Background Chronic Low Back Pain (CLBP) is a prevalent global health issue, leading to
prolonged discomfort and functional limitations. Hot spring hydrotherapy, which utilizes …

Ischemic heart disease (IHD) is the leading cause of mortality worldwide and can be
complicated by myocardial infarction (MI), leading to cardiac failure. Inorganic nitrite and …

Evidence for potential effects of inorganic nitrate (NO 3) on body weight is limited to
inconsistent findings of animal experiments. In this systematic review and meta-analysis, we …

Background Standard doses of second-generation H1-antihistamines (sgAHs) as first-line
treatment are not always effective in treating chronic spontaneous urticaria (CSU), and …