In several human malignant tumors of the urogenital tract, including cancers of the
endometrium, ovary, urinary bladder, and prostate, it has been possible to identify …

The crucial role of pituitary GnRH receptors (GnRH-R) in the control of reproductive
functions is well established. These receptors are the target of GnRH agonists (through …

Background Ovarian failure is a common toxic effect of chemotherapy. Studies of the use of
gonadotropin-releasing hormone (GnRH) agonists to protect ovarian function have shown …

Simple Summary Young women treated for breast cancer may experience early
menopause, which can negatively impact quality of life. The usual treatment for early …

Although significant progress has been made in the implementation of new breast cancer
treatments over the last three decades, this neoplasm annually continues to show high …

Introduction: Receptors for the luteinizing hormone-releasing hormone [LHRH, also known
as gonadotropin-releasing hormone (GnRH)] can be regarded as an ideal target for a …

Breast cancer is the most common malignancy in women worldwide, and ovarian cancer is
the most lethal gynecological malignancy. Women carrying a BRCA1/2 mutation have a very …

To establish an effective hormone receptor-based molecular classification of high-grade
serous ovarian cancer (HGSC), we retrospectively examined 875 consecutive HGSC …

Background Triple negative breast cancer (TNBC) is a distinct subtype of breast cancer
burdened with a dismal prognosis due to the lack of effective therapeutic agents. Receptors …

This paper presents the results of an experimental and computational study of the adhesion
of triptorelin-conjugated PEG-coated biosynthesized gold nanoparticles (GNP-PEG-TRP) to …