Among other mechanisms, oxidative stress has been postulated to play an important role in
the rate of ageing. Oxidative damage contributes to the hallmarks of ageing and essential …

Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

Atherosclerosis is a progressive disease in which endothelial cell dysfunction, macrophage
foam cell formation, and smooth muscle cell migration and proliferation, lead to the loss of …

The endothelium is immunoregulatory in that inhibiting the function of vascular adhesion
molecules blocks leukocyte recruitment and thus tissue inflammation. The function of …

The interplay between free radicals, antioxidants, and co-factors is important in maintaining
health, aging and age-related diseases. Free radicals induce oxidative stress, which is …

Our understanding of the role of vitamin E in human nutrition, health, and disease has
broadened and changed over the past two decades. Viewed initially as nature's most potent …

▪ Abstract Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in
the Western world. Its incidence has also been increasing lately in developing countries …

Cardiovascular diseases are a leading cause of mortality and morbidity worldwide, with
hypertension being a major risk factor. Numerous studies support the contribution of reactive …

Diabetes is a disease characterized by poor glycemic control for which risk of the type 2 form
increases with age. A rise in blood glucose concentration causes increased oxidative stress …

The familiar role of tocols (tocopherols and tocotrienols) as lipid-soluble chain-terminating
inhibitors of lipid peroxidation is currently in the midst of a reinterpretation. New biological …