[HTML][HTML] Clinical applications and anticancer effects of antimicrobial peptides: from bench to bedside
Cancer is a multifaceted global health issue and one of the leading causes of death
worldwide. In recent years, medical science has achieved great advances in the diagnosis …
worldwide. In recent years, medical science has achieved great advances in the diagnosis …
Inhalation delivery of repurposed drugs for lung cancer: approaches, benefits and challenges
Lung cancer (LC) is one of the leading causes of mortality accounting for almost 25% of
cancer deaths throughout the world. The shortfall of affordable and effective first-line …
cancer deaths throughout the world. The shortfall of affordable and effective first-line …
Nanoparticle‐mediated delivery of inhaled immunotherapeutics for treating lung metastasis
Q Jin, W Zhu, J Zhu, J Zhu, J Shen, Z Liu… - Advanced …, 2021 - Wiley Online Library
Despite the critical breakthrough achieved by immune checkpoint blockade (ICB), the
clinical benefits are usually restricted by inefficient infiltration of immune cells and immune …
clinical benefits are usually restricted by inefficient infiltration of immune cells and immune …
Magnetic particle targeting for diagnosis and therapy of lung cancers
M Saadat, MKD Manshadi, M Mohammadi… - Journal of Controlled …, 2020 - Elsevier
Over the past decade, the growing interest in targeted lung cancer therapy has guided
researchers toward the cutting edge of controlled drug delivery, particularly magnetic …
researchers toward the cutting edge of controlled drug delivery, particularly magnetic …
[HTML][HTML] Lipidic lyotropic liquid crystals: Insights on biomedical applications
G Blanco-Fernández, B Blanco-Fernandez… - Advances in Colloid and …, 2023 - Elsevier
Liquid crystals (LCs) possess unique physicochemical properties, translatable into a wide
range of applications. To date, lipidic lyotropic LCs (LLCs) have been extensively explored …
range of applications. To date, lipidic lyotropic LCs (LLCs) have been extensively explored …
[HTML][HTML] Repurposing non-oncology small-molecule drugs to improve cancer therapy: Current situation and future directions
L Fu, W Jin, J Zhang, L Zhu, J Lu, Y Zhen… - … Pharmaceutica Sinica B, 2022 - Elsevier
Drug repurposing or repositioning has been well-known to refer to the therapeutic
applications of a drug for another indication other than it was originally approved for …
applications of a drug for another indication other than it was originally approved for …
[HTML][HTML] Hepcidin upregulation in lung cancer: a potential therapeutic target associated with immune infiltration
Y Fan, B Liu, F Chen, Z Song, B Han, Y Meng… - Frontiers in …, 2021 - frontiersin.org
Lung cancer has the highest death rate among cancers globally. Hepcidin is a fascinating
regulator of iron metabolism; however, the prognostic value of hepcidin and its correlation …
regulator of iron metabolism; however, the prognostic value of hepcidin and its correlation …
Antimicrobial peptides as novel therapeutics for non-small cell lung cancer
NK Kunda - Drug discovery today, 2020 - Elsevier
Highlights•AMPs can selectively target and destroy cancer cells but not healthy cells.•AMPs
exhibit minimal systemic toxicity and minimal chance for acquiring resistance.•NSCLC cells …
exhibit minimal systemic toxicity and minimal chance for acquiring resistance.•NSCLC cells …
[HTML][HTML] Systematic development and optimization of inhalable pirfenidone liposomes for non-small cell lung cancer treatment
Non-small cell lung cancer (NSCLC) is a global disorder, treatment options for which remain
limited with resistance development by cancer cells and off-target events being major …
limited with resistance development by cancer cells and off-target events being major …
Tumor‐Tailored Ionizable Lipid Nanoparticles Facilitate IL‐12 Circular RNA Delivery for Enhanced Lung Cancer Immunotherapy
The advancement of message RNA (mRNA)‐based immunotherapies for cancer is highly
dependent on the effective delivery of RNA (Ribonucleic) payloads using ionizable lipid …
dependent on the effective delivery of RNA (Ribonucleic) payloads using ionizable lipid …