Viral diseases are one of the leading causes of morbidity and mortality in the world. Virus-
specific vaccines and antiviral drugs are the most powerful tools to combat viral diseases …

In 1947, Zika virus (ZIKV), a mosquito-borne flavivirus was identified in Uganda and
subsequently spread to Asia and the Pacific regions. In 2015, it was introduced in Brazil …

As of June 2020, the number of people infected with severe acute respiratory coronavirus 2
(SARS-CoV-2) continues to skyrocket, with more than 6.7 million cases worldwide. Both the …

The emerging SARS-CoV-2 infection associated with the outbreak of viral pneumonia in
China is ongoing worldwide. There are no approved antiviral therapies to treat this viral …

Combination therapies have become a standard for the treatment for HIV and hepatitis C
virus (HCV) infections. They are advantageous over monotherapies due to better efficacy …

Viruses are the major causes of acute and chronic infectious diseases in the world.
According to the World Health Organization, there is an urgent need for better control of viral …

Highlights•Drug repositioning is a cost-and time-efficient approach for new
indications.•Targeting host machineries, used by viruses, could develop broad-spectrum …

Viral envelope glycoproteins are crucial for viral infections. In the process of enveloped
viruses budding and release from the producer cells, viral envelope glycoproteins are …

The Zika virus (ZIKV) global epidemic prompted the World Health Organization to declare it
a 2016 Public Health Emergency of International Concern. The overwhelming experience …

Abstract Coronavirus disease 2019 (COVID-19) is an infective disease generated by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Given the pandemic urgency and …