Past, present, and future of deep brain stimulation: hardware, software, imaging, physiology and novel approaches

J Frey, J Cagle, KA Johnson, JK Wong… - Frontiers in …, 2022 - frontiersin.org
Deep brain stimulation (DBS) has advanced treatment options for a variety of neurologic and
neuropsychiatric conditions. As the technology for DBS continues to progress, treatment …

Deep brain stimulation programming 2.0: future perspectives for target identification and adaptive closed loop stimulation

F Hell, C Palleis, JH Mehrkens, T Koeglsperger… - Frontiers in …, 2019 - frontiersin.org
Deep brain stimulation has developed into an established treatment for movement disorders
and is being actively investigated for numerous other neurological as well as psychiatric …

[HTML][HTML] Lead-DBS v3. 0: Mapping deep brain stimulation effects to local anatomy and global networks

C Neudorfer, K Butenko, S Oxenford, N Rajamani… - Neuroimage, 2023 - Elsevier
Following its introduction in 2014 and with support of a broad international community, the
open-source toolbox Lead-DBS has evolved into a comprehensive neuroimaging platform …

[HTML][HTML] Superolateral medial forebrain bundle deep brain stimulation in major depression: a gateway trial

VA Coenen, BH Bewernick, S Kayser, H Kilian… - …, 2019 - nature.com
Short-and long-term antidepressant effects of deep brain stimulation (DBS) in treatment-
resistant depression (TRD) have been demonstrated for several brain targets in open-label …

Probabilistic mapping of deep brain stimulation: insights from 15 years of therapy

GJB Elias, A Boutet, SE Joel, J Germann… - Annals of …, 2021 - Wiley Online Library
Deep brain stimulation (DBS) depends on precise delivery of electrical current to target
tissues. However, the specific brain structures responsible for best outcome are still debated …

The dentato-rubro-thalamic tract as the potential common deep brain stimulation target for tremor of various origin: an observational case series

VA Coenen, B Sajonz, T Prokop, M Reisert, T Piroth… - Acta …, 2020 - Springer
Introduction Deep brain stimulation alleviates tremor of various origins. The dentato-rubro-
thalamic tract (DRT) has been suspected as a common tremor-reducing structure. Statistical …

Evaluation of methodologies for computing the deep brain stimulation volume of tissue activated

G Duffley, DN Anderson, J Vorwerk… - Journal of neural …, 2019 - iopscience.iop.org
Objective. Computational models are a popular tool for predicting the effects of deep brain
stimulation (DBS) on neural tissue. One commonly used model, the volume of tissue …

[HTML][HTML] Local neuroanatomical and tract-based proxies of optimal subcallosal cingulate deep brain stimulation

GJB Elias, J Germann, A Boutet, ME Beyn, P Giacobbe… - Brain stimulation, 2023 - Elsevier
Background Deep brain stimulation of the subcallosal cingulate area (SCC-DBS) is a
promising neuromodulatory therapy for treatment-resistant depression (TRD). Biomarkers of …

Local and distant cortical responses to single pulse intracranial stimulation in the human brain are differentially modulated by specific stimulation parameters

AC Paulk, R Zelmann, B Crocker, AS Widge… - Brain stimulation, 2022 - Elsevier
Background Electrical neuromodulation via direct electrical stimulation (DES) is an
increasingly common therapy for a wide variety of neuropsychiatric diseases. Unfortunately …

StimVision v2: Examples and applications in subthalamic deep brain stimulation for Parkinson's disease

AM Noecker, AM Frankemolle-Gilbert, B Howell… - … : Technology at the …, 2021 - Elsevier
Objective Subthalamic deep brain stimulation (DBS) is an established therapy for
Parkinson's disease. Connectomic DBS modeling is a burgeoning subfield of research …