The parasitophorous vacuole is a unique replicative niche for apicomplexan parasites,
including Toxoplasma gondii. Derived from host plasma membrane, the vacuole is rendered …

In Toxoplasma gondii, dense granules are known as the storage secretory organelles of the
so-called GRA proteins (for dense granule proteins), which are destined to the …

Toxoplasma gondii is a parasitic protist infecting a wide group of warm-blooded animals,
ranging from birds to humans. While this infection is usually asymptomatic in healthy …

The inner membrane complex (IMC) of Toxoplasma gondii is a peripheral membrane system
that is composed of flattened alveolar sacs that underlie the plasma membrane, coupled to a …

Apicomplexans employ a peripheral membrane system called the inner membrane complex
(IMC) for critical processes such as host cell invasion and daughter cell formation. We have …

Toxoplasma gondii is a master manipulator capable of effectively siphoning the resources
from the host cell for its intracellular subsistence. However, the molecular underpinnings of …

Toxoplasma gondii is an obligate intracellular parasite that invades host cells and replicates
within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite …

Toxoplasma gondii evades host immunity to establish a chronic infection. Here, we
assessed the role of parasitophorous vacuole (PV) membrane (PVM)-and intravacuolar …

The Toxoplasma inner membrane complex (IMC) is a unique organelle that plays critical
roles in parasite motility, invasion, egress, and replication. The IMC is delineated into the …

Infection by Toxoplasma gondii leads to massive changes to the host cell. Here, we identify
a novel host cell effector export pathway that requires the Golgi-resident aspartyl protease 5 …