Within the superfamily of pentameric ligand-gated ion channels, cholinergic nicotinic
receptors (nAChRs) were classically identified to mediate synaptic transmission in the …

Nicotinic acetylcholine receptors (nAChRs) are a subfamily of pentameric ligand-gated ion
channels with members identified in most eumetazoan clades. In vertebrates, they are …

Striatin-interacting protein 1 (Strip1) is a core component of the striatin interacting
phosphatase and kinase (STRIPAK) complex, which is involved in embryogenesis and …

Naked mole-rats are highly vocal, eusocial, subterranean rodents with, counterintuitively,
poor hearing. The causes underlying their altered hearing are unknown. Moreover, whether …

Rhodopsin, the light-sensitive visual pigment expressed in rod photoreceptors, is
specialized for vision in dim-light environments. Aquatic environments are particularly …

The expansion and pruning of ion channel families has played a crucial role in the evolution
of nervous systems. Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion …

Auditory sensation in the mammalian inner ear requires mechanosensitive hair cells and an
elaborate array of molecules that form the sensory transduction machinery. Several …

The mechanosensory lateral line is a hair cell-based system that is unique to craniates but
shows multiple losses in different species. It is thought to be evolutionary related to the …

Each sense serves a different specific function in spatial perception, and they all form a joint
multisensory spatial representation. For instance, hearing enables localization in the entire …

After the transition to life on land, tympanic middle ears emerged separately in different
groups of tetrapods, facilitating the efficient detection of airborne sounds and paving the way …