Toxicity of Doxorubicin (Dox) to different experimental organ systems

A Pugazhendhi, TNJI Edison, BK Velmurugan… - Life sciences, 2018 - Elsevier
Doxorubicin (Dox) is a valuable anticancer drug for hematologic and solid tumors. Yet, it can
cause multi-organ toxicities in various patients. Since toxicity evaluation is a major criterion …

Hydroxytyrosol: Bioavailability, toxicity, and clinical applications

M Robles-Almazan, M Pulido-Moran… - Food Research …, 2018 - Elsevier
Many beneficial properties have been attributed to the Mediterranean diet. Over the years,
researchers have attempted to learn which foods and which food components are …

Promising health benefits of the strawberry: a focus on clinical studies

S Afrin, M Gasparrini… - Journal of agricultural …, 2016 - ACS Publications
The potential health benefits associated with dietary intake of fruits have attracted increasing
interest. Among berries, the strawberry is a rich source of several nutritive and non-nutritive …

The healthy effects of strawberry polyphenols: which strategy behind antioxidant capacity?

TY Forbes-Hernandez, M Gasparrini… - Critical reviews in …, 2016 - Taylor & Francis
Current evidence indicates that the consumption of strawberries, a natural source of a wide
range of nutritive and bioactive compounds, is associated with the prevention and …

The roles of strawberry and honey phytochemicals on human health: A possible clue on the molecular mechanisms involved in the prevention of oxidative stress and …

M Battino, F Giampieri, D Cianciosi, J Ansary, X Chen… - Phytomedicine, 2021 - Elsevier
Background Oxidative stress and inflammation contribute to the etiopathogenesis of several
human chronic diseases, such as cancer, diabetes, cardiovascular diseases and metabolic …

Calcium Peroxide-Based Nanosystem with Cancer Microenvironment-Activated Capabilities for Imaging Guided Combination Therapy via Mitochondrial Ca2+ …

Q Sun, B Liu, R Zhao, L Feng, Z Wang… - … Applied Materials & …, 2021 - ACS Publications
Mitochondria are the “power plant” of the cell, providing a constant source of energy, and are
involved in a variety of intracellular signaling pathways. Among these pathways, Ca2+ …

Anthocyanins: From plant pigments to health benefits at mitochondrial level

V Bendokas, K Skemiene, S Trumbeckaite… - Critical Reviews in …, 2020 - Taylor & Francis
Anthocyanins are water-soluble pigments providing certain color for various plant parts,
especially in edible berries. Earlier these compounds were only known as natural food …

Select polyphenol-rich berry consumption to defer or deter diabetes and diabetes-related complications

A Hameed, M Galli, E Adamska-Patruno, A Krętowski… - Nutrients, 2020 - mdpi.com
Berries are considered “promising functional fruits” due to their distinct and ubiquitous
therapeutic contents of anthocyanins, proanthocyanidins, phenolic acids, flavonoids …

Natural bioactive compounds-doxorubicin combinations targeting topoisomerase II-alpha: Anticancer efficacy and safety

A Elfadadny, RF Ragab, R Hamada… - Toxicology and Applied …, 2023 - Elsevier
Cancer is one of the leading causes of death worldwide, so pursuing effective and safe
therapeutics for cancer is a key research objective nowadays. Doxorubicin (DOX) is one of …

Phosphorus and iron deficiencies induce a metabolic reprogramming and affect the exudation traits of the woody plant Fragaria×ananassa

F Valentinuzzi, Y Pii, G Vigani… - Journal of …, 2015 - academic.oup.com
Strawberries are a very popular fruit among berries, for both their commercial and economic
importance, but especially for their beneficial effects for human health. However, their …