Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research

X Tong, R Tang, M Xiao, J Xu, W Wang… - Journal of hematology & …, 2022 - Springer
Many types of human cells self-destruct to maintain biological homeostasis and defend the
body against pathogenic substances. This process, called regulated cell death (RCD), is …

Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy

W Gao, X Wang, Y Zhou, X Wang, Y Yu - Signal transduction and …, 2022 - nature.com
In recent years, immunotherapy represented by immune checkpoint inhibitors (ICIs) has led
to unprecedented breakthroughs in cancer treatment. However, the fact that many tumors …

Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency

Z Li, X Lai, S Fu, L Ren, H Cai, H Zhang, Z Gu… - Advanced …, 2022 - Wiley Online Library
Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …

Mito‐bomb: targeting mitochondria for cancer therapy

X Guo, N Yang, W Ji, H Zhang, X Dong… - Advanced …, 2021 - Wiley Online Library
Cancer has been one of the most common life‐threatening diseases for a long time.
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …

Ferroptosis, necroptosis, and pyroptosis in anticancer immunity

R Tang, J Xu, B Zhang, J Liu, C Liang, J Hua… - Journal of hematology & …, 2020 - Springer
In recent years, cancer immunotherapy based on immune checkpoint inhibitors (ICIs) has
achieved considerable success in the clinic. However, ICIs are significantly limited by the …

Two-pronged strategy of biomechanically active and biochemically multifunctional hydrogel wound dressing to accelerate wound closure and wound healing

M Li, Y Liang, J He, H Zhang, B Guo - Chemistry of Materials, 2020 - ACS Publications
A two-pronged strategy of biomechanically active and biochemically functional hydrogel
wound dressing which can assist wound closure and have multiple functions to promote …

Advances in nanomaterial-mediated photothermal cancer therapies: toward clinical applications

HS Han, KY Choi - Biomedicines, 2021 - mdpi.com
Photothermal therapy (PTT) has attracted extensive research attention as a noninvasive and
selective treatment strategy for numerous cancers. PTT functions via photothermal effects …

Mitochondrial adaptation in cancer drug resistance: prevalence, mechanisms, and management

P Jin, J Jiang, L Zhou, Z Huang, EC Nice… - Journal of Hematology & …, 2022 - Springer
Drug resistance represents a major obstacle in cancer management, and the mechanisms
underlying stress adaptation of cancer cells in response to therapy-induced hostile …

Nanoagent‐promoted mild‐temperature photothermal therapy for cancer treatment

G Gao, X Sun, G Liang - Advanced Functional Materials, 2021 - Wiley Online Library
Photothermal therapy (PTT), which utilizes near‐infrared light‐absorbing agents to ablate
tumor, has emerged as a highly promising anticancer strategy and received intensive …

Phenolic-enabled nanotechnology: versatile particle engineering for biomedicine

D Wu, J Zhou, MN Creyer, W Yim, Z Chen… - Chemical Society …, 2021 - pubs.rsc.org
Phenolics are ubiquitous in nature and have gained immense research attention because of
their unique physiochemical properties and widespread industrial use. In recent decades …