Development of the human placenta
MY Turco, A Moffett - Development, 2019 - journals.biologists.com
The placenta is essential for normal in utero development in mammals. In humans, defective
placental formation underpins common pregnancy disorders such as pre-eclampsia and …
placental formation underpins common pregnancy disorders such as pre-eclampsia and …
[HTML][HTML] Endometrial causes of recurrent pregnancy losses: endometriosis, adenomyosis, and chronic endometritis
P Pirtea, E Cicinelli, R De Nola, D de Ziegler… - Fertility and sterility, 2021 - Elsevier
Chronic inflammatory processes affecting the endometrium, as encountered in
endometriosis, adenomyosis, and chronic endometritis, alter endometrial receptivity. These …
endometriosis, adenomyosis, and chronic endometritis, alter endometrial receptivity. These …
Endometrial receptivity markers, the journey to successful embryo implantation
H Achache, A Revel - Human reproduction update, 2006 - academic.oup.com
Human embryo implantation is a three-stage process (apposition, adhesion and invasion)
involving synchronized crosstalk between a receptive endometrium and a functional …
involving synchronized crosstalk between a receptive endometrium and a functional …
Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this …
Y Zhou, CH Damsky, SJ Fisher - The Journal of clinical …, 1997 - Am Soc Clin Investig
In human pregnancy, placental cytotrophoblasts that invade the uterus downregulate the
expression of adhesion receptors that are characteristic of their epithelial origin, and …
expression of adhesion receptors that are characteristic of their epithelial origin, and …
Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction
BACKGROUND The placenta is the functional interface between the mother and the fetus
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …
Etiology and pathogenesis of preeclampsia: current concepts
GA Dekker, BM Sibai - American journal of obstetrics and gynecology, 1998 - Elsevier
The etiology of preeclampsia is unknown. At present, 4 hypotheses are the subject of
extensive investigation, as follows:(1) Placental ischemia—Increased trophoblast …
extensive investigation, as follows:(1) Placental ischemia—Increased trophoblast …
Regulation of human placental development by oxygen tension
O Genbacev, Y Zhou, JW Ludlow, SJ Fisher - Science, 1997 - science.org
Cytotrophoblasts, specialized placental cells, proliferate early in pregnancy and then
differentiate into tumor-like cells that establish blood flow to the placenta by invading the …
differentiate into tumor-like cells that establish blood flow to the placenta by invading the …
Implantation and the placenta: key pieces of the development puzzle
The mammalian embryo cannot develop without the placenta. Its specialized cells
(trophoblast, endoderm, and extraembryonic mesoderm) form early in development. They …
(trophoblast, endoderm, and extraembryonic mesoderm) form early in development. They …
Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?
Y Zhou, SJ Fisher, M Janatpour… - The Journal of …, 1997 - Am Soc Clin Investig
Establishment of the human placenta requires that fetal cytotrophoblast stem cells in
anchoring chorionic villi become invasive. These cytotrophoblasts aggregate into cell …
anchoring chorionic villi become invasive. These cytotrophoblasts aggregate into cell …
Embryo implantation
A lesson learned from modern developmental biology is the striking degree of conservation
of strategies and molecules used to program developmental events in species as diverse as …
of strategies and molecules used to program developmental events in species as diverse as …