Hypoxia is a known feature of solid tumors and a critical promoter of tumor hallmarks.
Hypoxia influences tumor immunity in a way favoring immune evasion and resistance …

Spinal cord injury (SCI) occurs when the spinal cord is damaged from either a traumatic
event or disease. SCI is characterised by multiple injury phases that affect the transmission …

NLRP3 inflammasome is a part of the innate immune system and responsible for the rapid
identification and eradication of pathogenic microbes, metabolic stress products, reactive …

Introduction Increased neutrophil extracellular trap (NET) formation has been reported to be
associated with cerebrovascular dysfunction and neurological deficits in traumatic brain …

Objectives This study aimed to evaluate the expression of cytosine monophosphate kinase 2
(CMPK2) and activation of the NLRP3 inflammasome in rats with spinal cord injury (SCI) and …

Spinal cord injury (SCI) is a significant public health issue that imposes numerous burdens
on patients and society. Uncontrolled excessive inflammation in the second pathological …

As a double-stranded DNA (dsDNA) sensor, the PYHIN family member absent in melanoma
2 (AIM2) is an essential component of the inflammasome families. Activation of AIM2 by …

Inflammasome activation and the consequent release of pro-inflammatory cytokines play a
crucial role in the development of sensory/motor deficits following spinal cord injury (SCI) …

Spinal cord injury (SCI) is a sudden onset of disruption to the spinal neural tissue, leading to
loss of motor control and sensory function of the body. Oxidative stress is considered a …

Previous studies have shown that Biochanin A, a flavonoid compound with estrogenic
effects, can serve as a neuroprotective agent in the context of cerebral ischemia/reperfusion …