Natural products: A lead for drug discovery and development

B Chopra, AK Dhingra - Phytotherapy Research, 2021 - Wiley Online Library
Natural products are used since ancient times in folklore for the treatment of various
ailments. Plant‐derived products have been recognized for many years as a source of …

Antibacterial activities of medicinal plants used in Mexican traditional medicine

A Sharma, R del Carmen Flores-Vallejo… - Journal of …, 2017 - Elsevier
Ethnopharmacological relevance We provide an extensive summary of the in vitro
antibacterial properties of medicinal plants popularly used in Mexico to treat infections, and …

Medicinal plants in Mexico: Healers' consensus and cultural importance

M Heinrich, A Ankli, B Frei, C Weimann… - Social science & …, 1998 - Elsevier
Medicinal plants are an important element of indigenous medical systems in Mexico. These
resources are usually regarded as part of a culture's traditional knowledge. This study …

[PDF][PDF] The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IκB kinase

BHB Kwok, B Koh, MKI Ndubuisi, M Elofsson… - Chemistry & biology, 2001 - cell.com
Background: Biologically active natural products continue to be useful in the exploration and
control of intracellular signaling processes. For example, the sesquiterpene lactone …

Medicinal plants used in the traditional management of diabetes and its sequelae in Central America: A review

P Giovannini, MJR Howes, SE Edwards - Journal of ethnopharmacology, 2016 - Elsevier
Ethnopharmacological relevance Globally 387 million people currently have diabetes and it
is projected that this condition will be the 7th leading cause of death worldwide by 2030. As …

Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF‐κB

PM Bork, ML Schmitz, M Kuhnt, C Escher… - FEBS …, 1997 - Wiley Online Library
The potential inhibitory effect of 54 Mexican Indian medicinal plants on the activation of
transcription factor NF‐κB was studied. Band‐shift experiments identified the ethanolic leaf …

Ethnopharmacology of Mexican asteraceae (compositae)

M Heinrich, M Robles, JE West… - Annual Review of …, 1998 - annualreviews.org
▪ Abstract Traditional herbal remedies have increased in popularity in Europe and the United
States in recent years but have always been important to people living in rural Mexico and to …

Natural products as targeted modulators of the nuclear factor‐KB pathway

P Bremner, M Heinrich - Journal of Pharmacy and …, 2002 - Wiley Online Library
The use of plant extracts to alleviate inflammatory diseases is centuries old and continues to
this day. This review assesses the current understanding of the use of such plants and …

Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation

K De Bosscher, ML Schmitz… - Proceedings of the …, 1997 - National Acad Sciences
Glucocorticoids exert multiple anti-inflammatory activities, one of which is the inhibition of
transcription dependent on the nuclear factor (NF)-κB. It has been suggested that the effect …

Medical ethnobotany of the Zapotecs of the Isthmus-Sierra (Oaxaca, Mexico): Documentation and assessment of indigenous uses

B Frei, M Baltisberger, O Sticher, M Heinrich - Journal of …, 1998 - Elsevier
The Zapotec inhabitants of the Sierra de Oaxaca foothills (Mexico) live in an area of great
botanic diversity. In daily subsistence and in response to illness, plants play a major role. An …