Virus-like particles: Revolutionary platforms for developing vaccines against emerging infectious diseases
Virus-like particles (VLPs) are nanostructures that possess diverse applications in
therapeutics, immunization, and diagnostics. With the recent advancements in biomedical …
therapeutics, immunization, and diagnostics. With the recent advancements in biomedical …
Synthetic biology for bioengineering virus‐like particle vaccines
HK Charlton Hume, J Vidigal… - Biotechnology and …, 2019 - Wiley Online Library
Vaccination is the most effective method of disease prevention and control. Many viruses
and bacteria that once caused catastrophic pandemics (eg, smallpox, poliomyelitis …
and bacteria that once caused catastrophic pandemics (eg, smallpox, poliomyelitis …
Solutions against emerging infectious and noninfectious human diseases through the application of baculovirus technologies
AM Targovnik, JA Simonin, GJ Mc Callum… - Applied microbiology …, 2021 - Springer
Baculoviruses are insect pathogens widely used as biotechnological tools in different fields
of life sciences and technologies. The particular biology of these entities (biosafety viruses 1; …
of life sciences and technologies. The particular biology of these entities (biosafety viruses 1; …
Challenges in the development of egg-independent vaccines for influenza
Introduction: Current influenza vaccines are mainly produced from viruses propagated in
eggs, an established process developed over 70 years. However, this technology presents …
eggs, an established process developed over 70 years. However, this technology presents …
Membrane‐based approach for the downstream processing of influenza virus‐like particles
Currently, marketed influenza vaccines are only efficient against homologous viruses, thus
requiring a seasonal update based on circulating subtypes. This constant reformulation …
requiring a seasonal update based on circulating subtypes. This constant reformulation …
Biochemical monitoring throughout all stages of rabies virus-like particles production by Raman spectroscopy using global models
LGO Guardalini, PE da Silva Cavalcante, J Leme… - Journal of …, 2023 - Elsevier
This work aimed to quantify growth and biochemical parameters (viable cell density, Xv; cell
viability, CV; glucose, lactate, glutamine, glutamate, ammonium, and potassium …
viability, CV; glucose, lactate, glutamine, glutamate, ammonium, and potassium …
Comparison of chemometric models using Raman spectroscopy for offline biochemical monitoring throughout the VLP-making upstream process
This work aimed to compare the predictive capacity of linear (Partial Least Squares;
Principal Component Regression) and non-linear (Artificial Neural Network, ANN; Support …
Principal Component Regression) and non-linear (Artificial Neural Network, ANN; Support …
Downstream processing for influenza vaccines and candidates: An update
S B. Carvalho, C Peixoto… - Biotechnology and …, 2021 - Wiley Online Library
Seasonal and pandemic influenza outbreaks present severe health and economic burdens.
To overcome limitations on influenza vaccines' availability and effectiveness, researchers …
To overcome limitations on influenza vaccines' availability and effectiveness, researchers …
Purification of influenza virus‐like particles using sulfated cellulose membrane adsorbers
ABSTRACT BACKGROUND Vaccines based on virus‐like particles (VLPs) are an
alternative to inactivated viral vaccines that combine good safety profiles with strong …
alternative to inactivated viral vaccines that combine good safety profiles with strong …
Dendritic cells/macrophages-targeting feature of Ebola glycoprotein and its potential as immunological facilitator for antiviral vaccine approach
In the prevention of epidemic and pandemic viral infection, the use of the antiviral vaccine
has been the most successful biotechnological and biomedical approach. In recent times …
has been the most successful biotechnological and biomedical approach. In recent times …