Platelet-rich plasma (PRP) has been introduced and applied to a wide spectrum of acute
and chronic ligament and tendon pathologic conditions. Although the biological effect of …

Several tendon and ligament animal models were presented at the 2022 Orthopaedic
Research Society Tendon Section Conference held at the University of Pennsylvania, May 5 …

Objective It has been debated whether the onset of knee osteoarthritis is initiated in cartilage
or subchondral bone. The purpose of this study was to clarify the effects of increasing or …

Background Mechanical loading is purported to restore ligament biomechanics post-injury.
But this is difficult to corroborate in clinical research when key ligament tissue properties (eg …

Objective Abnormal joint instability contributes to cartilage damage and osteophyte
formation. We investigated whether controlling joint instability inhibited chronic synovial …

Objective Abnormal joint movement is associated with osteoarthritis (OA). Previous studies
using the controlling abnormal joint movement (CAJM) model of OA reported delayed …

Aim The healing ability of the anterior cruciate ligament (ACL) injury is very poor; however, it
has recently been shown to undergo self-healing with conservative treatments. In this study …

Cartilage degeneration is the main pathological component of knee osteoarthritis (OA), but
no effective treatment for its control exists. Although exercise can inhibit OA, the abnormal …

Summary Objective The Anterior Cruciate Ligament (ACL)-deficient model helps to clarify
the mechanism of knee osteoarthritis (OA); however, the conventional ACL injury model …

Objective Osteoarthritis (OA) is induced by accumulated mechanical stress to joints;
however, little has been reported regarding the cause among detailed mechanical stress on …