[HTML][HTML] Progress in antitumor mechanisms and applications of phenformin
Q Zhong, D Li, XP Yang - Oncology Reports, 2024 - spandidos-publications.com
Phenformin, a biguanide compound, has attracted increased attention due to its prominent
antitumor activity. As a multi‑target agent, the antitumor effects of phenformin involve a wide …
antitumor activity. As a multi‑target agent, the antitumor effects of phenformin involve a wide …
[HTML][HTML] The role of glycolysis in tumorigenesis: From biological aspects to therapeutic opportunities
M Cordani, F Michetti, A Zarrabi, A Zarepour, C Rumio… - Neoplasia, 2024 - Elsevier
Glycolytic metabolism generates energy and intermediates for biomass production. Tumor-
associated glycolysis is upregulated compared to normal tissues in response to tumor cell …
associated glycolysis is upregulated compared to normal tissues in response to tumor cell …
Cysteine protease inhibitor 1 promotes metastasis by mediating an oxidative phosphorylation/MEK/ERK axis in esophageal squamous carcinoma cancer
L Zhang, X Chen, J Wang, M Chen, J Chen… - Scientific Reports, 2024 - nature.com
Abstract Cysteine protease inhibitor 1 (CST1) is a cystatin superfamily protein that inhibits
cysteine protease activity and is reported to be involved in the development of many …
cysteine protease activity and is reported to be involved in the development of many …
A proton-catalyzing prodrug for PDT and glycolysis inhibition-synergistic therapy of tumor in spatiotemporal dimensions
M Li, X Sun, X Ma, Y Tan, X Jin, Y Wang, F Yang… - Science China …, 2024 - Springer
The reactive oxygen species (ROS) generation from photosensitizer in photodynamic
therapy (PDT) is limited by tumor hypoxia. Even type-I photosensitizers, eg, sulfur …
therapy (PDT) is limited by tumor hypoxia. Even type-I photosensitizers, eg, sulfur …
Cell Metabolism Therapy by Small Natural Compounds
S Nesci, A Spagnoletta, F Oppedisano - International Journal of …, 2023 - mdpi.com
Cellular metabolism therapy counteracting metabolic dysfunction performs a preeminent
role in the pathophysiology of different diseases, such as cancer, diabetes, metabolic …
role in the pathophysiology of different diseases, such as cancer, diabetes, metabolic …
CST1 promotes the metastasis by mediating an oxidative phosphorylation/MEK/ERK axis in esophageal squamous carcinoma cancer
L Zhang, X Chen, J Wang, M Chen, W Zhuang, Y Xia… - 2023 - researchsquare.com
Abstract Cysteine Protease Inhibitor 1 (CST1), a cystatin superfamily protein with the effect
on the inhibition of cysteine protease activity, is reported to be involved in the development …
on the inhibition of cysteine protease activity, is reported to be involved in the development …
[PDF][PDF] Research News. Publications, 2020. Volume 4
S Majumdar - 2020 - egrove.olemiss.edu
23. Eissa IH, Ibrahim MK, Metwaly AM, Belal A, Mehany ABM, Abdelhady AA, Elhendawy
MA, Radwan MM, ElSohly MA, Mahdy HA. Design, molecular docking, in vitro, and in vivo …
MA, Radwan MM, ElSohly MA, Mahdy HA. Design, molecular docking, in vitro, and in vivo …