Ecto-nucleotidases play a pivotal role in purinergic signal transmission. They hydrolyze
extracellular nucleotides and thus can control their availability at purinergic P2 receptors …

The involvement of extracellular nucleotides and adenosine in an array of cell-specific
responses has long been known and appreciated, but the integrative view of purinergic …

Extracellular nucleotides and nucleosides mediate diverse signaling effects in virtually all
organs and tissues. Most models of purinergic signaling depend on functional interactions …

Coffee is a drink prepared from roasted coffee beans and is lauded for its aroma and flavour.
It is the third most popular beverage in the world. This beverage is known by its stimulant …

P2 receptors that are activated by extracellular nucleotides (eg, ATP, ADP, UTP, UDP, Ap n
A) and P1 receptors activated by adenosine control a diversity of biological processes. The …

Background and purpose: ARL 67156, 6‐N, N‐Diethyl‐d‐β‐γ‐dibromomethylene adenosine
triphosphate, originally named FPL 67156, is the only commercially available inhibitor of …

Several lines of evidence show that serum alkaline phosphatase (AP) is not only a signpost
of cholestasis but also a surrogate marker of the severity of primary biliary cirrhosis and …

The first comprehensive review of the ubiquitous “ecto-ATPases” by Plesner was published
in 1995. A year later, a lymphoid cell activation antigen, CD39, that had been cloned …

Extracellular nucleotides, including ATP, are essential regulators of liver function and serve
as danger signals that trigger inflammation upon injury. Ectonucleotidases, which are …

Purinergic signalling is involved in both the physiology and pathophysiology of the liver.
Hepatocytes, Kupffer cells, vascular endothelial cells and smooth muscle cells, stellate cells …