Non-natural folded polymers (foldamers) display considerable versatility, and the design of
such molecules is of great current interest. In this respect, peptidic foldamers are perhaps …

The self‐assembly of different classes of peptide, including cyclic peptides, amyloid peptides
and surfactant‐like peptides into nanotube structures is reviewed. The modes of self …

The construction of bioactive peptides using β-amino acid-containing sequence patterns is a
very promising strategy to obtain analogues that exhibit properties of high interest for …

β-Sheet forming self assembling cyclic peptides offer a versatile scaffold for the construction
and control of hydrogen-bonded nanotube assemblies. These structures have major …

Compounds containing a CÀF bond present improved properties (ie hydrophobicity,
solubility, metabolic stability) compared to their corresponding CÀH counterparts, thus …

The remarkable complexity of globular protein structures was first revealed about half a
century ago, when the crystal structure of myoglobin was determined at 2.4 Å. 1 In the …

The stereoselective synthesis of syn-β-fluoroaziridine building blocks via chiral aryl iodide-
catalyzed fluorination of allylic amines is reported. The method employs HF–pyridine as a …

Biosynthetic modification of nonribosomal peptide backbones represents a potentially
powerful strategy to modulate the structure and properties of an important class of …

The number of neuropeptides and their corresponding receptors has increased steadily over
the last fourty years: initially, peptides were isolated from gut or brain (eg, Substance P …

Small cyclic peptides possess a wide range of biological properties and unique structures
that make them attractive to scientists working in a range of areas from medicinal to …